Comment on “Lack of Association Found between Helicobacter pylori Infection and Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Retrospective Study”
المؤلف
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-1، 1ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-11
دولة النشر
مصر
عدد الصفحات
1
التخصصات الرئيسية
الملخص EN
We have read with great interest the paper written by Feng Xiong et al.
“Lack of Association Found between Helicobacter pylori Infection and Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Retrospective Study” [1].
From the beginning, possible association between H.
pylori infection and diarrhea-predominant irritable bowel syndrome (IBS-D) was a challenging topic among clinicians [2].
In this paper, authors concluded that no significant correlation between H.
pylori infection and IBS-D was reported.
Moreover, IBS-D patients may not benefit from H.
pylori eradication.
Apart from being an interesting study, there is a short list of critical points to draw a better conclusion within such multicenter studies worldwide.
(1) Sample size is mainly lacking in this study.
Relatively high rate of treatment efficacy observed in H.
pylori infected group can be bound to the low number of investigated individuals.
(2) Lack of long-term follow-up in this study is leading to incorrect conclusion regarding relieving bloating symptoms.
Moreover, insufficient study design for treatment of the bacterium was another pitfall causing not strong conclusion.
According to the current findings, authors concluded that IBS-D patients do not benefit from H.
pylori eradication.
As a note, determination of successful H.
pylori eradication is not clearly described and validated in this study.
Also, we need a long-term follow-up (at least 6 months) to confirm primary conclusion drawn by the authors.
(3) With regard to the current findings, to be honest, it seems that we have a lack of better evidence rather than lack of association.
In conclusion, we agree with Xiong et al., if proven in further studies, about the underlying mechanisms determining H.
pylori role in IBS.
Finally, the understanding of the H.
pylori-host interaction in IBS subjects may open the insight into the development of new therapeutic interventions to manage H.
pylori associated extra-digestive disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Talebi Bezmin Abadi, Amin. 2016. Comment on “Lack of Association Found between Helicobacter pylori Infection and Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Retrospective Study”. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-1.
https://search.emarefa.net/detail/BIM-1104729
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Talebi Bezmin Abadi, Amin. Comment on “Lack of Association Found between Helicobacter pylori Infection and Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Retrospective Study”. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-1.
https://search.emarefa.net/detail/BIM-1104729
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Talebi Bezmin Abadi, Amin. Comment on “Lack of Association Found between Helicobacter pylori Infection and Diarrhea-Predominant Irritable Bowel Syndrome: A Multicenter Retrospective Study”. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-1.
https://search.emarefa.net/detail/BIM-1104729
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104729
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر