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Characteristics and Risk Factors of Helicobacter pylori Associated Gastritis: A Prospective Cross-Sectional Study in Northeast Thailand
المؤلفون المشاركون
Tongtawee, Taweesak
Kaewpitoon, Soraya
Dechsukhum, Chavaboon
Matrakool, Likit
Kaewpitoon, Natthawut
Loyd, Ryan A.
Panpimanmas, Sukij
Leeanansaksiri, Wilairat
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background and Aim.
Risk factors for Helicobacter pylori infection are genetic susceptibility and poor living conditions.
This study aimed to investigate the Mdm2 gene, clarithromycin resistance, and possible risk factors for Helicobacter pylori infection.
Methods.
Risk factors and clinical characteristics were analyzed, including patient demographic data, patient income, personal history, possible source of transmission, patient symptoms, endoscopic findings, patterns of clarithromycin resistance, and patterns of Mdm2 SNIP309.
Results.
Ingestion of pickled fish (OR = 11.27, 95% CI = 4.31–29.45, p<0.0001), salt crab (OR = 8.83, 95% CI = 1.99–39.14, p<0.001), and Papaya salad (OR = 8.73, 95% CI = 4.54–16.79, p<0.01).
The prevalence of clarithromycin resistance was 56% (wild type, A2143/2142A, is 23.8%; mutation, A2143/2142CG, is 35.7%; wild type + mutation is 40.5%).
The genetic polymorphisms of Mdm2 SNIP309 were SNIP309 T/T homozygous in 78%, SNIP309 G/T heterozygous in 19%, and SNIP309 G/G homozygous in 3%.
Conclusion.
Pickled fish, salt crab, and Papaya salad are positive risk factors.
There was high prevalence of clarithromycin resistance.
The Mdm2 SNIP309 G/G homozygous genotype might be a risk factor for gastric cancer and the fact that it is infrequent in Thailand.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tongtawee, Taweesak& Kaewpitoon, Soraya& Kaewpitoon, Natthawut& Dechsukhum, Chavaboon& Leeanansaksiri, Wilairat& Loyd, Ryan A.…[et al.]. 2016. Characteristics and Risk Factors of Helicobacter pylori Associated Gastritis: A Prospective Cross-Sectional Study in Northeast Thailand. Gastroenterology Research and Practice،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104827
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tongtawee, Taweesak…[et al.]. Characteristics and Risk Factors of Helicobacter pylori Associated Gastritis: A Prospective Cross-Sectional Study in Northeast Thailand. Gastroenterology Research and Practice Vol. 2016, no. 2016 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1104827
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tongtawee, Taweesak& Kaewpitoon, Soraya& Kaewpitoon, Natthawut& Dechsukhum, Chavaboon& Leeanansaksiri, Wilairat& Loyd, Ryan A.…[et al.]. Characteristics and Risk Factors of Helicobacter pylori Associated Gastritis: A Prospective Cross-Sectional Study in Northeast Thailand. Gastroenterology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104827
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104827
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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