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Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus
المؤلفون المشاركون
Zhao, Dian-dian
Jiao, Pei-lin
Yu, Jing-jia
Wang, Xiao-jing
Zhao, Lin
Xuan, Yan
Sun, Li-hao
Tao, Bei
Wang, Wei-qing
Ning, Guang
Liu, Jian-min
Zhao, Hong-yan
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-28
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Accumulating evidence suggests that oxidative stress is associated with osteoporosis.
Serum uric acid (UA) is a strong endogenous antioxidant.
Therefore, we investigated the relationship between the serum UA and BMD in Chinese men with T2DM.
In this cross-sectional study of 621 men with T2DM, BMDs at lumbar spine (L2–4), femoral neck (FN), and total hip (TH) were measured by dual-energy X-ray absorptiometry (DXA).
Serum levels of UA, calcium (Ca), 25-OH vitamin D3 (vitD3), parathyroid hormone (PTH), and creatinine (Cr) were also tested.
Data analyses revealed that serum UA levels were positively associated with BMD at all sites ( p < 0.05 ) in men with T2DM after adjusting for multiple confounders.
The serum UA levels were positively correlated with body weight ( r = 0.322 ), body mass index (BMI) ( r = 0.331 ), Ca ( r = 0.179 ), and Cr ( r = 0.239 ) ( p < 0.001 ) and were also positively associated with the concentrations of PTH ( r = 0.10 , p < 0.05 ).
When compared with those in the lowest tertile of UA levels, men with T2DM in the highest tertile had a lower prevalence of osteoporosis or osteopenia (adjusted odds ratio 0.54, 95% confidence interval [CI] 0.31–0.95).
These data suggest that higher serum levels of UA are associated with higher BMDs and lower risks of osteoporosis in Chinese men with T2DM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhao, Dian-dian& Jiao, Pei-lin& Yu, Jing-jia& Wang, Xiao-jing& Zhao, Lin& Xuan, Yan…[et al.]. 2016. Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1105827
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhao, Dian-dian…[et al.]. Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus. International Journal of Endocrinology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1105827
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhao, Dian-dian& Jiao, Pei-lin& Yu, Jing-jia& Wang, Xiao-jing& Zhao, Lin& Xuan, Yan…[et al.]. Higher Serum Uric Acid Is Associated with Higher Bone Mineral Density in Chinese Men with Type 2 Diabetes Mellitus. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1105827
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1105827
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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