Intrahepatic Fat Content and Markers of Hepatic Fibrosis in Obese Children
المؤلفون المشاركون
Wu, Wei
Zhang, Hongxi
Xu, Xiaoqin
Huang, Ke
Fu, Junfen
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-04
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Aim.
We evaluated both direct and indirect hepatic fibrosis markers in obese children and their relationship with intrahepatic fat (IHF) content.
We also aimed to investigate the possible roles of IHF and fibrosis markers in metabolic syndrome (MS).
Methods.
189 obese children were divided into simple obese (SOB), simple steatosis (SS), and nonalcoholic steatohepatitis (NASH) groups according to their IHF and blood alanine transaminase (ALT) levels.
They were also scored for the MS components.
IHF was assessed as a continuous variable by proton magnetic resonance spectroscopy (1H-MRS).
In addition, 30 nonobese children were enrolled as controls and their direct hepatic fibrosis markers and IHF were assessed.
Results.
Age was related to IHF, NFS, and FIB-4.
Both NFS and APRI were related to IHF more significantly than the direct markers.
In the estimation of liver function impairment, indirect markers had greater AUROC than direct markers.
In MS, IHF and all the fibrosis markers showed similar AUROC.
Conclusions.
Both direct and indirect markers played a valuable role in evaluating MS.
Indirect markers were more effective in distinguishing fatty hepatitis.
Age is an important factor underlying hepatic steatosis and fibrosis even in children.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Wei& Zhang, Hongxi& Xu, Xiaoqin& Huang, Ke& Fu, Junfen. 2016. Intrahepatic Fat Content and Markers of Hepatic Fibrosis in Obese Children. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1105899
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Wei…[et al.]. Intrahepatic Fat Content and Markers of Hepatic Fibrosis in Obese Children. International Journal of Endocrinology No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1105899
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Wei& Zhang, Hongxi& Xu, Xiaoqin& Huang, Ke& Fu, Junfen. Intrahepatic Fat Content and Markers of Hepatic Fibrosis in Obese Children. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1105899
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1105899
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر