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The Frequency of Langerhans Islets β-Cells Autoantibodies (Anti-GAD) in Georgian Children and Adolescents with Chronic Autoimmune Thyroiditis
المؤلفون المشاركون
Giorgadze, Elene
Balakhadze, Mariam
Lomidze, Marina
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-27
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Aim.
Chronic autoimmune thyroiditis and type 1 diabetes mellitus are organ-specific autoimmune diseases.
There is large evidence that autoimmunity against the thyroid gland in patients with type 1 diabetes mellitus is increased, but little is known about anti-islet cell autoimmune status in patients with chronic autoimmune thyroiditis.
We evaluated the concentration of antibodies against glutamic acid decarboxylase (GAD) which are widely used as a diagnostic and predictive tool for type 1 diabetes mellitus, in school-aged Georgian children with chronic autoimmune thyroiditis.
Methods.
The frequency of anti-GAD antibodies was measured in Georgian school-aged children with chronic autoimmune thyroiditis and compared to healthy age and sex matched controls.
Results.
Of the 41 patients with chronic autoimmune thyroiditis 4 (9.8%) were positive for GAD antibodies.
The frequency of GAD positivity in the chronic autoimmune thyroiditis group was significantly higher than in the control subjects ( P = 0.036 ).
Conclusion.
In the study we found that the frequency of GAD antibody positivity in autoimmune thyroiditis patients was significantly higher (9.8%, P = 0.036 ) than in the control group.
Our findings support the concept that patients with autoimmune thyroid disease may develop type 1 diabetes mellitus in future life.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Balakhadze, Mariam& Giorgadze, Elene& Lomidze, Marina. 2016. The Frequency of Langerhans Islets β-Cells Autoantibodies (Anti-GAD) in Georgian Children and Adolescents with Chronic Autoimmune Thyroiditis. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1105954
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Balakhadze, Mariam…[et al.]. The Frequency of Langerhans Islets β-Cells Autoantibodies (Anti-GAD) in Georgian Children and Adolescents with Chronic Autoimmune Thyroiditis. International Journal of Endocrinology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1105954
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Balakhadze, Mariam& Giorgadze, Elene& Lomidze, Marina. The Frequency of Langerhans Islets β-Cells Autoantibodies (Anti-GAD) in Georgian Children and Adolescents with Chronic Autoimmune Thyroiditis. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1105954
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1105954
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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