Predictive Factors of Development of Graves’ Ophthalmopathy for Patients with Juvenile Graves’ Disease
المؤلفون المشاركون
Jarusaitiene, Dalia
Verkauskiene, Rasa
Jasinskas, Vytautas
Jankauskiene, J.
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-16
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Due to low incidence of Graves’ ophthalmopathy (GO) among children, the manifestation is poorly analyzed, posing a risk to late identification of insidious disease.
Purposes.
To identify predictive factors that may influence the development of GO in pediatric and young patients with Graves’ disease (GD).
Methods.
A cross-sectional study of patients newly diagnosed with pediatric or juvenile GD during 2002–2012 was conducted at the Hospital of Lithuanian University of Health Sciences.
Ocular evaluation was based on European Group on Graves’ Orbitopathy survey.
The ocular manifestations were analyzed in relation to demographic, environmental, and clinical factors.
Results.
In total, 130 patients with juvenile GD were included; 29.2% had GO.
Median age at GD onset was 17 yrs (IQR 4–29).
Main symptoms of GO were eyelids retraction (73.7%), proptosis (65.8%), injection of conjunctiva (42.1%), and eyeball motility disturbance (21.1%).
Major significant and independent risk factors for GO development were high initial concentration of FT4 (OR = 5.963), TTHAb (OR = 6.358), stress (OR = 6.030), and smoking (OR = 7.098).
Conclusion.
The major factors that could influence GO development were smoking, stress, and increased levels of initial TRAb, FT4.
Slight proptosis, retraction of eyelids, and conjunctive injection were found as predominant ophthalmological symptoms in juvenile GO.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jarusaitiene, Dalia& Verkauskiene, Rasa& Jasinskas, Vytautas& Jankauskiene, J.. 2016. Predictive Factors of Development of Graves’ Ophthalmopathy for Patients with Juvenile Graves’ Disease. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1106002
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jarusaitiene, Dalia…[et al.]. Predictive Factors of Development of Graves’ Ophthalmopathy for Patients with Juvenile Graves’ Disease. International Journal of Endocrinology No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1106002
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jarusaitiene, Dalia& Verkauskiene, Rasa& Jasinskas, Vytautas& Jankauskiene, J.. Predictive Factors of Development of Graves’ Ophthalmopathy for Patients with Juvenile Graves’ Disease. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1106002
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106002
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر