Serum Adiponectin Level as a Predictor of Subclinical Cushing’s Syndrome in Patients with Adrenal Incidentaloma
المؤلفون المشاركون
Dogruk Unal, Asli
Ayturk, Semra
Aldemir, Derya
Bascil Tutuncu, Neslihan
المصدر
International Journal of Endocrinology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-30
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Subclinical Cushing’s syndrome (SCS) is a condition of slight but chronic cortisol excess in patients with adrenal incidentaloma (AI) without typical signs and symptoms of Cushing’s syndrome.
Adiponectin has potent roles in modulating energy balance and metabolic homeostasis and acts in opposition to glucocorticoids.
This study aimed to evaluate adiponectin level in SCS and nonfunctional AI (NAI) patients and its relation with metabolic parameters.
Patients with AI ( n = 40 ) and metabolically healthy controls ( n = 30 ) were included.
In AI patients and controls, detailed medical history assessment, physical examinations, anthropometric measurements, and laboratory measurements were performed.
Age, body mass index, waist circumference, and lipid profiles were significantly higher and waist-to-hip ratio and adiponectin level were significantly lower in the AI patients than in the controls.
The midnight cortisol and urinary free cortisol levels were significantly higher in the SCS patients ( n = 8 ) than in the NAI patients ( n = 32 ).
Adiponectin level of the SCS group was significantly lower than those of the NAI and control groups.
The sensitivity and specificity for an adiponectin level of ≤13.00 ng/mL in predicting the presence of SCS were 87.5% and 77.4%, respectively.
In conclusion, adiponectin is valuable in predicting the presence of SCS in AI patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dogruk Unal, Asli& Ayturk, Semra& Aldemir, Derya& Bascil Tutuncu, Neslihan. 2016. Serum Adiponectin Level as a Predictor of Subclinical Cushing’s Syndrome in Patients with Adrenal Incidentaloma. International Journal of Endocrinology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1106026
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dogruk Unal, Asli…[et al.]. Serum Adiponectin Level as a Predictor of Subclinical Cushing’s Syndrome in Patients with Adrenal Incidentaloma. International Journal of Endocrinology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1106026
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dogruk Unal, Asli& Ayturk, Semra& Aldemir, Derya& Bascil Tutuncu, Neslihan. Serum Adiponectin Level as a Predictor of Subclinical Cushing’s Syndrome in Patients with Adrenal Incidentaloma. International Journal of Endocrinology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1106026
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106026
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر