Integrating Genomic Data Sets for Knowledge Discovery: An Informed Approach to Management of Captive Endangered Species

المؤلفون المشاركون

Irizarry, Kristopher J. L.
Bryant, Doug
Kalish, Jordan
Eng, Curtis
Schmidt, Peggy L.
Barrett, Gini
Barr, Margaret C.

المصدر

International Journal of Genomics

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2016-06-08

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الأحياء

الملخص EN

Many endangered captive populations exhibit reduced genetic diversity resulting in health issues that impact reproductive fitness and quality of life.

Numerous cost effective genomic sequencing and genotyping technologies provide unparalleled opportunity for incorporating genomics knowledge in management of endangered species.

Genomic data, such as sequence data, transcriptome data, and genotyping data, provide critical information about a captive population that, when leveraged correctly, can be utilized to maximize population genetic variation while simultaneously reducing unintended introduction or propagation of undesirable phenotypes.

Current approaches aimed at managing endangered captive populations utilize species survival plans (SSPs) that rely upon mean kinship estimates to maximize genetic diversity while simultaneously avoiding artificial selection in the breeding program.

However, as genomic resources increase for each endangered species, the potential knowledge available for management also increases.

Unlike model organisms in which considerable scientific resources are used to experimentally validate genotype-phenotype relationships, endangered species typically lack the necessary sample sizes and economic resources required for such studies.

Even so, in the absence of experimentally verified genetic discoveries, genomics data still provides value.

In fact, bioinformatics and comparative genomics approaches offer mechanisms for translating these raw genomics data sets into integrated knowledge that enable an informed approach to endangered species management.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Irizarry, Kristopher J. L.& Bryant, Doug& Kalish, Jordan& Eng, Curtis& Schmidt, Peggy L.& Barrett, Gini…[et al.]. 2016. Integrating Genomic Data Sets for Knowledge Discovery: An Informed Approach to Management of Captive Endangered Species. International Journal of Genomics،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1106146

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Irizarry, Kristopher J. L.…[et al.]. Integrating Genomic Data Sets for Knowledge Discovery: An Informed Approach to Management of Captive Endangered Species. International Journal of Genomics No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1106146

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Irizarry, Kristopher J. L.& Bryant, Doug& Kalish, Jordan& Eng, Curtis& Schmidt, Peggy L.& Barrett, Gini…[et al.]. Integrating Genomic Data Sets for Knowledge Discovery: An Informed Approach to Management of Captive Endangered Species. International Journal of Genomics. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1106146

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1106146