The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis
المؤلفون المشاركون
Mohammadpoorasl, Asghar
Rangboo, Vajiheh
Noroozi, Mostafa
Zavoshy, Roza
Rezadoost, Seyed Amirmansoor
المصدر
International Journal of Hepatology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-11
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Based on recent basic and clinical investigations, the extract of artichoke (Cynara scolymus) leaf has been revealed to be used for hepatoprotective and cholesterol reducing purposes.
We aimed to assess the therapeutic effects of artichoke on biochemical and liver biomarkers in patients with nonalcoholic steatohepatitis (NASH).
Methods.
In a randomized double blind clinical trial, 60 consecutive patients suffering NASH were randomly assigned to receive Cynara scolymus extract (as 6 tablets per day consisting of 2700 mg extract of the herb) as the intervention group or placebo as the control group for two months.
Results.
Comparing changes in study markers following interventions showed improvement in liver enzymes.
The levels of triglycerides and cholesterol were significantly reduced in the group treated with Cynara scolymus when compared to placebo group.
To compare the role of Cynara scolymus use with placebo in changes in study parameters, multivariate linear regression models were employed indicating higher improvement in liver enzymes and also lipid profile particularly triglycerides and total cholesterol following administration of Cynara scolymus in comparison with placebo use.
Conclusion.
This study sheds light on the potential hepatoprotective activity and hypolipidemic effect of Cynara scolymus in management of NASH.
This clinical trial is registered in the IRCT, Iranian Registry of Clinical Trials, by number IRCT2014070218321N1.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rangboo, Vajiheh& Noroozi, Mostafa& Zavoshy, Roza& Rezadoost, Seyed Amirmansoor& Mohammadpoorasl, Asghar. 2016. The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis. International Journal of Hepatology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106214
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rangboo, Vajiheh…[et al.]. The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis. International Journal of Hepatology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1106214
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rangboo, Vajiheh& Noroozi, Mostafa& Zavoshy, Roza& Rezadoost, Seyed Amirmansoor& Mohammadpoorasl, Asghar. The Effect of Artichoke Leaf Extract on Alanine Aminotransferase and Aspartate Aminotransferase in the Patients with Nonalcoholic Steatohepatitis. International Journal of Hepatology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1106214
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106214
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر