BK Virus Load Associated with Serum Levels of sCD30 in Renal Transplant Recipients
المؤلفون المشاركون
Shamran, Haidar A.
Kareem, Abdulameer
Malik, Salma N.
Jawad, Rana S.
المصدر
International Journal of Microbiology
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-09
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Rejection is the main drawback facing the renal transplant operations.
Complicated and overlapping factors, mainly related to the immune system, are responsible for this rejection.
Elevated serum levels of sCD30 were frequently recorded as an indicator for renal allograft rejection, while BV virus is considered as one of the most serious consequences for immunosuppressive treatment of renal transplant recipients (RTRs).
Aims.
This study aimed to determine the association of BK virus load with serum levels of sCD30 in RTRs suffering from nephropathy.
Patients and Methods.
A total of 50 RTRs with nephropathy and 30 age-matched apparently healthy individuals were recruited for this study.
Serum samples were obtained from each participant.
Real-time PCR was used to quantify BK virus load in RTRs serum, while ELISA technique was employed to estimate serum levels of sCD30.
Results.
Twenty-two percent of RTRs had detectable BKV with mean viral load of 1.094E + 06 ± 2.291E + 06.
RTRs showed higher mean serum level of sCD30 (20.669±18.713 U/mL) than that of controls (5.517±5.304 U/mL) with significant difference.
BK virus load had significant positive correlation with the serum levels of sCD30 in RTRs group.
Conclusion.
These results suggest that serum levels of sCD30 could be used as an indicator of BK viremia, and accordingly the immunosuppressive regime should be adjusted.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shamran, Haidar A.& Malik, Salma N.& Kareem, Abdulameer& Jawad, Rana S.. 2016. BK Virus Load Associated with Serum Levels of sCD30 in Renal Transplant Recipients. International Journal of Microbiology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106298
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shamran, Haidar A.…[et al.]. BK Virus Load Associated with Serum Levels of sCD30 in Renal Transplant Recipients. International Journal of Microbiology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1106298
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shamran, Haidar A.& Malik, Salma N.& Kareem, Abdulameer& Jawad, Rana S.. BK Virus Load Associated with Serum Levels of sCD30 in Renal Transplant Recipients. International Journal of Microbiology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1106298
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1106298
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر