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Determining the Optimal Duration of Progesterone Supplementation prior to Transfer of Cryopreserved Embryos and Its Impact on Implantation and Pregnancy Rates: A Pilot Study
المؤلفون المشاركون
المصدر
International Journal of Reproductive Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-26
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To determine the optimal duration of progesterone supplementation prior to transfer of cryopreserved embryos and its impact on implantation and pregnancy rates.
Study Design.
Prospective randomised study.
Materials and Methods.
In an IVF unit of a tertiary centre, sixty-six patients undergoing cryopreserved embryo transfer cycles were included.
Endometrial preparation was done with estradiol valerate.
Once it reached a minimum of 7 mm, patients were allocated randomly into group I ( n = 39 ) and group II ( n = 27 ).
Injectable progesterone 100 mg daily was then started for 3 and 4 days, respectively.
This was followed by transfer of at least one thawed cleavage stage day 2 embryo of good quality.
Groups I and II were compared in terms of clinical pregnancy and implantation rates.
Results.
In group I (3-day progesterone) and group II (4-day progesterone) the pregnancy rates were 41.02% (16/39) and 18.51% (5/27), respectively.
On the other hand, the implantation rates were 16.82% (18/107) and 7.69% (6/78), respectively.
The difference was statistically significant ( p values 0.0172 and 0.0386, resp.).
Conclusion.
Progesterone supplementation for three days before the transfer of cleavage stage (day 2) cryopreserved embryos has significantly higher pregnancy and implantation rates, as compared to four-day supplementation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sharma, Sangita& Majumdar, Abha. 2016. Determining the Optimal Duration of Progesterone Supplementation prior to Transfer of Cryopreserved Embryos and Its Impact on Implantation and Pregnancy Rates: A Pilot Study. International Journal of Reproductive Medicine،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107065
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sharma, Sangita& Majumdar, Abha. Determining the Optimal Duration of Progesterone Supplementation prior to Transfer of Cryopreserved Embryos and Its Impact on Implantation and Pregnancy Rates: A Pilot Study. International Journal of Reproductive Medicine No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1107065
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sharma, Sangita& Majumdar, Abha. Determining the Optimal Duration of Progesterone Supplementation prior to Transfer of Cryopreserved Embryos and Its Impact on Implantation and Pregnancy Rates: A Pilot Study. International Journal of Reproductive Medicine. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107065
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1107065
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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