Heavy Alcohol Drinking Associated Akathisia and Management with Quetiapine XR in Alcohol Dependent Patients
المؤلفون المشاركون
Kurlawala, Zimple
Vatsalya, Vatsalya
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-25
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Heavy drinking contributes to involuntary body movements such as akathisia.
Quetiapine has been shown to alleviate symptoms of akathisia; however, its efficacy in the alcohol dependent population is not well established.
Thus, we aimed to identify efficacy of Quetiapine in treating akathisia in very heavy drinking alcohol dependent patients.
108 male and female heavy alcohol consuming study participants received 13 weeks of Quetiapine XR.
Drinking history (Timeline Followback, TLFB), depression (Montgomery-Asberg Depression Rating Scale, MADRS), and movement (Barnes Akathisia Scale, BARS) measures were collected at baseline (0 W), week 6 (6 W), and week 12 (12 W).
The role of drinking, symptoms of depression, and efficacy of Quetiapine for treating akathisia were assessed.
In patients with no symptoms of depression (low MADRS), Quetiapine treatment decreased symptoms of akathisia.
Patients with clinically significant depression (high MADRS) reported a significant increase in akathisia measures at 6 W which eventually decreased at 12 W to below baseline levels.
The increase in akathisia at 6 W corresponded with a significant increase in the patients’ total drinks and heavy drinking pattern.
Treatment with Quetiapine progressively lowered the occurrence of akathisia in alcohol dependent patients who do not show symptoms of depression.
Quetiapine treatment lowered akathisia over time in heavy drinkers who had clinically significant symptoms of depression.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kurlawala, Zimple& Vatsalya, Vatsalya. 2016. Heavy Alcohol Drinking Associated Akathisia and Management with Quetiapine XR in Alcohol Dependent Patients. Journal of Addiction،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107169
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kurlawala, Zimple& Vatsalya, Vatsalya. Heavy Alcohol Drinking Associated Akathisia and Management with Quetiapine XR in Alcohol Dependent Patients. Journal of Addiction No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1107169
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kurlawala, Zimple& Vatsalya, Vatsalya. Heavy Alcohol Drinking Associated Akathisia and Management with Quetiapine XR in Alcohol Dependent Patients. Journal of Addiction. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1107169
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1107169
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر