Analysis of E. rutaecarpa Alkaloids Constituents In Vitro and In Vivo by UPLC-Q-TOF-MS Combined with Diagnostic Fragment
المؤلفون المشاركون
Li, Yu-bo
Zhang, Yanjun
Hou, Zhiguo
Yang, Shenshen
Tian, Meng
Yuan, Lei
Deng, Haoyue
Wang, Lei
Li, Aizhu
المصدر
Journal of Analytical Methods in Chemistry
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Evodia rutaecarpa (Juss.) Benth.
(Rutaceae) dried ripe fruit is used for dispelling colds, soothing liver, and analgesia.
Pharmacological research has proved that alkaloids are the main active ingredients of E.
rutaecarpa.
This study aimed to rapidly classify and identify the alkaloids constituents of E.
rutaecarpa by using UPLC-Q-TOF-MS coupled with diagnostic fragments.
Furthermore, the effects of the material base of E.
rutaecarpa bioactive ingredients in vivo were examined such that the transitional components in the blood of rats intragastrically given E.
rutaecarpa were analyzed and identified.
In this study, the type of alcohol extraction of E.
rutaecarpa and the corresponding blood sample were used for the analysis by UPLC-Q-TOF-MS in positive ion mode.
After reviewing much of the literature and collected information on the fragments, we obtained some diagnostic fragments of the alkaloids.
Combining the diagnostic fragments with the technology of UPLC-Q-TOF-MS, we identified the compounds of E.
rutaecarpa and blood samples and compared the ion fragment information with that of the alkaloids in E.
rutaecarpa.
A total of 17 alkaloids components and 6 blood components were identified.
The proposed method was rapid, accurate, and sensitive.
Therefore, this technique can reliably and practically analyze the chemical constituents in traditional Chinese medicine (TCM).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Shenshen& Tian, Meng& Yuan, Lei& Deng, Haoyue& Wang, Lei& Li, Aizhu…[et al.]. 2016. Analysis of E. rutaecarpa Alkaloids Constituents In Vitro and In Vivo by UPLC-Q-TOF-MS Combined with Diagnostic Fragment. Journal of Analytical Methods in Chemistry،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1107314
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Shenshen…[et al.]. Analysis of E. rutaecarpa Alkaloids Constituents In Vitro and In Vivo by UPLC-Q-TOF-MS Combined with Diagnostic Fragment. Journal of Analytical Methods in Chemistry No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1107314
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Shenshen& Tian, Meng& Yuan, Lei& Deng, Haoyue& Wang, Lei& Li, Aizhu…[et al.]. Analysis of E. rutaecarpa Alkaloids Constituents In Vitro and In Vivo by UPLC-Q-TOF-MS Combined with Diagnostic Fragment. Journal of Analytical Methods in Chemistry. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1107314
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1107314
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر