Screening of Undiagnosed Hypothyroidism in Elderly Persons with Diabetes according to Age-Specific Reference Intervals for Serum Thyroid Stimulating Hormone and the Impact of Antidiabetes Drugs
المؤلفون المشاركون
Fontes, Rosita
Teixeira, Patricia de Fatima dos Santos
Vaisman, Mario
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-15
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Studies have suggested that hypothyroidism is more frequent in the elderly with diabetes mellitus.
However, an adaptation of TSH levels to age should be considered in this assessment.
Some antidiabetes drugs reportedly interfere with TSH levels.
The objectives of this study were to evaluate the prevalence of undiagnosed hypothyroidism in patients with diabetes and the influence of antidiabetes drugs.
Material and Methods.
1160 subjects, 60 years and older (751 with diabetes), were studied; results were compared according to diabetes treatment and with persons without diabetes.
TSH, FT4, antithyroperoxidase, fasting glucose, and HbA1c were measured.
Results and Discussion.
6.4% of patients with diabetes had hypothyroidism, a higher prevalence compared with persons without diabetes (5.1%), but lower than observed in many studies.
The use of age-specific TSH reference interval (RI) could explain this difference.
Patients taking metformin (MTF) had TSH (showed in medians) slightly lower (2.8 mU/L) than those not on MTF (3.3 mU/L), p < 0.05 .
MTF doses influenced TSH levels.
Conclusions.
The use of specific TSH RI could avoid the misdiagnosis of hypothyroidism in elderly with diabetes.
Patients in use of MTF as single drug had lower TSH than those using other medications and persons without diabetes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fontes, Rosita& Teixeira, Patricia de Fatima dos Santos& Vaisman, Mario. 2016. Screening of Undiagnosed Hypothyroidism in Elderly Persons with Diabetes according to Age-Specific Reference Intervals for Serum Thyroid Stimulating Hormone and the Impact of Antidiabetes Drugs. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107961
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fontes, Rosita…[et al.]. Screening of Undiagnosed Hypothyroidism in Elderly Persons with Diabetes according to Age-Specific Reference Intervals for Serum Thyroid Stimulating Hormone and the Impact of Antidiabetes Drugs. Journal of Diabetes Research No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1107961
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fontes, Rosita& Teixeira, Patricia de Fatima dos Santos& Vaisman, Mario. Screening of Undiagnosed Hypothyroidism in Elderly Persons with Diabetes according to Age-Specific Reference Intervals for Serum Thyroid Stimulating Hormone and the Impact of Antidiabetes Drugs. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1107961
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1107961
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر