Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity
المؤلفون المشاركون
Li, Xiao-Hong
Lin, Hai-Yan
Wang, Shu-Hua
Guan, Li-Ying
Wang, Yi-Bing
Cao, Y. Q.
Jiang, X. Y.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-01
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aims.
To examine whether fibrinogen levels are a valuable biomarker for assessing disease severity and monitoring disease progression in patients with diabetic foot ulcer (DFU).
Methods.
A retrospective study was designed to examine the utility of fibrinogen in estimating disease severity in patients with DFU admitted to our hospital between January 2015 and January 2016.
In total, 152 patients with DFU were enrolled in the study group, and 52 age and gender matched people with diabetes but no DFU were included as the control group.
DFU severity was assessed using Wagner criteria.
Results.
Patients with DFU were divided into 2 subgroups based on the Wagner criteria.
Mean fibrinogen values were significantly higher in patients with DFU grade ≧ 3 compared to those with DFU grades 1-2 (5.23 ± 1.37 g/L versus 3.61 ± 1.04 g/L).
Using ROC statistic, a cut-off value of 5.13 g/L indicated the possible amputation with a sensitivity of 81.8% and a specificity of 78.9% (positive predictive value [PPV] 78.6%, negative predictive value [89.0%]).
Fibrinogen values were found to be correlated with CRP levels, neutrophil, and WBC count.
Conclusions.
Fibrinogen levels might be a valuable tool for assessing the disease severity and monitoring the disease progression in patients with DFU.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Xiao-Hong& Guan, Li-Ying& Lin, Hai-Yan& Wang, Shu-Hua& Cao, Y. Q.& Jiang, X. Y.…[et al.]. 2016. Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1108011
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Xiao-Hong…[et al.]. Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity. Journal of Diabetes Research No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1108011
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Xiao-Hong& Guan, Li-Ying& Lin, Hai-Yan& Wang, Shu-Hua& Cao, Y. Q.& Jiang, X. Y.…[et al.]. Fibrinogen: A Marker in Predicting Diabetic Foot Ulcer Severity. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1108011
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108011
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر