The Burden of NAFLD and Its Characteristics in a Nationwide Population with Type 2 Diabetes
المؤلفون المشاركون
Giorda, Carlo
Forlani, Gabriele
Manti, Roberta
Mazzella, Natalia
De Cosmo, Salvatore
Rossi, Maria Chiara
Nicolucci, Antonio
Di Bartolo, Paolo
Ceriello, Antonio
Guida, Pietro
Study Group, AMD-Annals
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-30
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
We studied the prevalence of nonalcoholic fatty liver disease (NAFLD) and its clinical correlates in a population of patients with type 2 diabetes mellitus (T2DM).
Methods.
Clinical data of 94,577 T2DM patients were retrieved from 160 diabetes clinics in Italy in a standardized format and centrally analyzed anonymously.
After exclusion of 5967 cases (high or uncertain alcohol intake), in 38,880 the Fatty Liver Index (FLI) was used as a proxy for the diagnosis of NAFLD.
Factors associated with FLI assessed NAFLD (FLI-NAFLD) were evaluated through multivariate analysis.
Results.
FLI-NAFLD was present in 59.6% of patients.
Compared to non-NAFLD, FLI-NAFLD was associated with impairment in renal function, higher albumin excretion, HbA1c and blood pressure, lower HDL cholesterol, and poorer quality of care.
ALT was within normal limits in 73.6% of FLI-NAFLD patients (45.6% if the updated reference values were used).
The prevalence of FLI-NAFLD did not differ if the whole sample (94,577 cases) was examined, irrespective of alcohol intake.
Conclusions.
FLI-NAFLD was present in the majority of T2DM patients of our sample and metabolic derangement, not alcohol consumption, was mainly associated with the disease.
FLI-NAFLD patients have a worse metabolic profile.
ALT levels are not predictive of NAFLD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Forlani, Gabriele& Giorda, Carlo& Manti, Roberta& Mazzella, Natalia& De Cosmo, Salvatore& Rossi, Maria Chiara…[et al.]. 2016. The Burden of NAFLD and Its Characteristics in a Nationwide Population with Type 2 Diabetes. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108041
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Forlani, Gabriele…[et al.]. The Burden of NAFLD and Its Characteristics in a Nationwide Population with Type 2 Diabetes. Journal of Diabetes Research No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1108041
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Forlani, Gabriele& Giorda, Carlo& Manti, Roberta& Mazzella, Natalia& De Cosmo, Salvatore& Rossi, Maria Chiara…[et al.]. The Burden of NAFLD and Its Characteristics in a Nationwide Population with Type 2 Diabetes. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108041
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108041
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر