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Association between Serum Cystatin C and Diabetic Foot Ulceration in Patients with Type 2 Diabetes: A Cross-Sectional Study
المؤلفون المشاركون
Liang, Ziwen
Zhao, Jie
Deng, Wuquan
Zhang, Yuping
Zheng, Yanling
Zhou, Lina
Boey, Johnson
Yang, Gangyi
Chen, Bing
Armstrong, David G.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-07
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Serum cystatin C (CysC) has been identified as a possible potential biomarker in a variety of diabetic complications, including diabetic peripheral neuropathy and peripheral artery disease.
We aimed to examine the association between CysC and diabetic foot ulceration (DFU) in patients with type 2 diabetes (T2D).
411 patients with T2D were enrolled in this cross-sectional study at a university hospital.
Clinical manifestations and biochemical parameters were compared between DFU group and non-DFU group.
The association between serum CysC and DFU was explored by binary logistic regression analysis.
The cut point of CysC for DFU was also evaluated by receiver operating characteristic (ROC) curve.
The prevalence of coronary artery disease, diabetic nephropathy (DN), and DFU dramatically increased with CysC ( P < 0.01 ) in CysC quartiles.
Multivariate logistic regression analysis indicated that the significant risk factors for DFU were serum CysC, coronary artery disease, hypertension, insulin use, the differences between supine and sitting TcPO2, and hypertension.
ROC curve analysis revealed that the cut point of CysC for DFU was 0.735 mg/L.
Serum CysC levels correlated with DFU and severity of tissue loss.
Our study results indicated that serum CysC was associated with a high prevalence of DFU in Chinese T2D subjects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhao, Jie& Deng, Wuquan& Zhang, Yuping& Zheng, Yanling& Zhou, Lina& Boey, Johnson…[et al.]. 2016. Association between Serum Cystatin C and Diabetic Foot Ulceration in Patients with Type 2 Diabetes: A Cross-Sectional Study. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108261
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhao, Jie…[et al.]. Association between Serum Cystatin C and Diabetic Foot Ulceration in Patients with Type 2 Diabetes: A Cross-Sectional Study. Journal of Diabetes Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108261
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhao, Jie& Deng, Wuquan& Zhang, Yuping& Zheng, Yanling& Zhou, Lina& Boey, Johnson…[et al.]. Association between Serum Cystatin C and Diabetic Foot Ulceration in Patients with Type 2 Diabetes: A Cross-Sectional Study. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108261
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108261
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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