The Relationship of Metabolic Syndrome Traits with Beta-Cell Function and Insulin Sensitivity by Oral Minimal Model Assessment in South Asian and European Families Residing in the Netherlands
المؤلفون المشاركون
Geragotou, Thekla
Jainandunsing, Sjaam
Özcan, Behiye
de Rooij, Felix W. M.
Tentolouris, Nicholas
Sijbrands, Eric J. G.
Kokkinos, Alexander
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-11
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
There are different metabolic syndrome traits among patients with different ethnicities.
Methods.
We investigated this by studying 44 South Asians and 54 Europeans and classified them in three groups according to the occurrence of metabolic syndrome (MetS) and Type 2 Diabetes (T2D).
Insulin sensitivity index (ISI), static, dynamic, and total beta-cell responsivity indices ( Φ ), and disposition indices (DIs) were calculated with the use of oral minimal model (OMM).
Results.
In both ethnicities, ISI was lower in the subgroup with MetS and T2D as compared to the subgroup without MetS nor T2D ( P < 0.004 ).
South Asians without MetS were more insulin resistant than Europeans without MetS ( P = 0.033 ).
In the South Asians, ISI, dynamic DI, and static DI were associated significantly ( P < 0.006 ) with high-density lipoprotein cholesterol and triglycerides.
In the Europeans, ISI was associated with waist-to-hip ratio ( P = 0.005 ) and systolic and diastolic blood pressure ( P < 0.005 ), while static DI was related to the systolic blood pressure ( P = 0.005 ).
Conclusions.
MetS was linked with insulin resistance and reduced capacity to handle glucose regardless of ethnicity.
ISI and DIs were associated with lipid traits in South Asians and with blood pressure in Europeans suggesting that insulin resistance enhances different metabolic syndrome traits among different ethnicities.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Geragotou, Thekla& Jainandunsing, Sjaam& Özcan, Behiye& de Rooij, Felix W. M.& Kokkinos, Alexander& Tentolouris, Nicholas…[et al.]. 2016. The Relationship of Metabolic Syndrome Traits with Beta-Cell Function and Insulin Sensitivity by Oral Minimal Model Assessment in South Asian and European Families Residing in the Netherlands. Journal of Diabetes Research،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108324
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Geragotou, Thekla…[et al.]. The Relationship of Metabolic Syndrome Traits with Beta-Cell Function and Insulin Sensitivity by Oral Minimal Model Assessment in South Asian and European Families Residing in the Netherlands. Journal of Diabetes Research No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1108324
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Geragotou, Thekla& Jainandunsing, Sjaam& Özcan, Behiye& de Rooij, Felix W. M.& Kokkinos, Alexander& Tentolouris, Nicholas…[et al.]. The Relationship of Metabolic Syndrome Traits with Beta-Cell Function and Insulin Sensitivity by Oral Minimal Model Assessment in South Asian and European Families Residing in the Netherlands. Journal of Diabetes Research. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108324
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108324
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر