Levels of Urinary Metabolites of Organophosphate Flame Retardants, TDCIPP, and TPHP, in Pregnant Women in Shanghai
المؤلفون المشاركون
Zhang, Junfeng
Feng, Liping
Ouyang, Fengxiu
Liu, Liangpo
Wang, Xu
Wang, Xia
Shen, Heqing
Zhang, Jun Jim
Li, Yi-Ju
Murtha, Amy P.
المصدر
Journal of Environmental and Public Health
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-25
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Flame retardants are widely used in consumer products to reduce their flammability.
Previously used flame retardants have been sequentially banned due to their environmental and human toxicity.
Currently, tris(1,3-dichloropropyl) phosphate (TDCIPP) and triphenyl phosphate (TPHP) are among the most commonly used flame retardants.
TDCIPP and TPHP are reproductive toxins and have carcinogenic, neurotoxic, and endocrine-disrupting properties.
Although high levels of TDCIPP and TPHP have been found in drinking water, seawater, and office air in China, data regarding human exposure are lacking.
In this study, we assessed the level of urinary TPHP and TDCIPP metabolites (DPHP and BDCIPP, resp.) in a cohort of pregnant women (N=23) from Shanghai, China, using liquid chromatography-tandem mass spectrometry.
DPHP were detected in 100% urine samples, while only four urine samples had detectable level of BDCIPP in this cohort (17% detected).
Geometric means of DPHP and BDCIPP concentrations were 1.1 ng/mL (interquartile range [IQR]: 0.6, 1.5 ng/mL) and 1.2 ng/mL (IQR: 0.6, 2.2 ng/mL), respectively.
In this small cohort, urinary DPHP and BDCIPP levels were not significantly correlated with miscarriages, neonatal birthweight, gestational diabetes, or maternal age.
These data suggest that exposure to TPHP is widespread, and they demonstrate the feasibility of using urinary biomarkers to measure exposures to modern flame-retardant chemicals.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Feng, Liping& Ouyang, Fengxiu& Liu, Liangpo& Wang, Xu& Wang, Xia& Li, Yi-Ju…[et al.]. 2016. Levels of Urinary Metabolites of Organophosphate Flame Retardants, TDCIPP, and TPHP, in Pregnant Women in Shanghai. Journal of Environmental and Public Health،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108550
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Feng, Liping…[et al.]. Levels of Urinary Metabolites of Organophosphate Flame Retardants, TDCIPP, and TPHP, in Pregnant Women in Shanghai. Journal of Environmental and Public Health No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108550
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Feng, Liping& Ouyang, Fengxiu& Liu, Liangpo& Wang, Xu& Wang, Xia& Li, Yi-Ju…[et al.]. Levels of Urinary Metabolites of Organophosphate Flame Retardants, TDCIPP, and TPHP, in Pregnant Women in Shanghai. Journal of Environmental and Public Health. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108550
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108550
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر