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The Impact of T Cell Vaccination in Alleviating and Regulating Systemic Lupus Erythematosus Manifestation
المؤلفون المشاركون
Yang, Yuan
Huang, Liuye
Wei, Dapeng
Li, Wanyi
Yin, Qin
Pang, Juan
Zhang, Zhongwei
Kuang, Yu
المصدر
Journal of Immunology Research
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-04
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
Systemic lupus erythematosus (SLE) is an autoimmune disease identified by a plethora of production of autoantibodies.
Autoreactive T cells may play an important role in the process.
Attenuated T cell vaccination (TCV) has proven to benefit some autoimmune diseases by deleting or suppressing pathogenic T cells.
However, clinical evidence for TCV in SLE is still limited.
Therefore, this self-controlled study concentrates on the clinical effects of TCV on SLE patients.
Methods.
16 patients were enrolled in the study; they accepted TCV regularly.
SLEDAI, clinical symptoms, blood parameters including complements 3 and 4 levels, ANA, and anti-ds-DNA antibodies were tested.
In addition, the side effects and drug usage were observed during the patients’ treatment and follow-up.
Results.
Remissions in clinical symptoms such as facial rash, vasculitis, and proteinuria were noted in most patients.
There are also evident reductions in SLEDAI, anti-ds-DNA antibodies, and GC dose and increases in C3 and C4 levels, with no pathogenic side effects during treatment and follow-up.
Conclusions.
T cell vaccination is helpful in alleviating and regulating systemic lupus erythematosus manifestation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Liuye& Yang, Yuan& Kuang, Yu& Wei, Dapeng& Li, Wanyi& Yin, Qin…[et al.]. 2016. The Impact of T Cell Vaccination in Alleviating and Regulating Systemic Lupus Erythematosus Manifestation. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108812
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Liuye…[et al.]. The Impact of T Cell Vaccination in Alleviating and Regulating Systemic Lupus Erythematosus Manifestation. Journal of Immunology Research No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1108812
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Liuye& Yang, Yuan& Kuang, Yu& Wei, Dapeng& Li, Wanyi& Yin, Qin…[et al.]. The Impact of T Cell Vaccination in Alleviating and Regulating Systemic Lupus Erythematosus Manifestation. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1108812
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108812
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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