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In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity
المؤلفون المشاركون
Guidetti, Gianandrea
Di Cerbo, Alessandro
Giovazzino, Angela
Rubino, Valentina
Palatucci, Anna Teresa
Centenaro, Sara
Fraccaroli, Elena
Cortese, Laura
Bonomo, Maria Grazia
Ruggiero, Giuseppina
Canello, Sergio
Terrazzano, Giuseppe
المصدر
Journal of Immunology Research
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-15
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Several extrinsic factors, like drugs and chemicals, can foster autoimmunity.
Tetracyclines, in particular oxytetracycline (OTC), appear to correlate with the emergence of immune-mediated diseases.
Accumulation of OTC, the elective drug for gastrointestinal and respiratory infectious disease treatment in broiler chickens, was reported in chicken edible tissues and could represent a potential risk for pets and humans that could assume this antibiotic as residue in meat or in meat-derived byproducts.
We investigated the in vitro anti-inflammatory properties of a pool of thirteen botanicals as a part of a nutraceutical diet, with proven immunomodulatory activity.
In addition, we evaluated the effect of such botanicals in contrasting the in vitro proinflammatory toxicity of OTC.
Our results showed a significant reduction in interferon- (INF-) γ production by human and canine lymphocytes in presence of botanicals ( p ⁎ < 0.05 ).
Increased INF-γ production, dependent on 24-hour OTC-incubation of T lymphocytes, was significantly reduced by the coincubation with Haematococcus pluvialis, with Glycine max, and with the mix of all botanicals ( p ⁎ < 0.05 ).
In conclusion, the use of these botanicals was shown to be able to contrast OTC-toxicity and could represent a new approach for the development of functional foods useful to enhance the standard pharmacological treatment in infections as well as in preventing or reducing the emergence of inflammatory diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guidetti, Gianandrea& Di Cerbo, Alessandro& Giovazzino, Angela& Rubino, Valentina& Palatucci, Anna Teresa& Centenaro, Sara…[et al.]. 2016. In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108822
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guidetti, Gianandrea…[et al.]. In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity. Journal of Immunology Research No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1108822
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guidetti, Gianandrea& Di Cerbo, Alessandro& Giovazzino, Angela& Rubino, Valentina& Palatucci, Anna Teresa& Centenaro, Sara…[et al.]. In Vitro Effects of Some Botanicals with Anti-Inflammatory and Antitoxic Activity. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108822
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108822
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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