Safety and Efficacy Profile of Commercial Veterinary Vaccines against Rift Valley Fever: A Review Study
المؤلف
المصدر
Journal of Immunology Research
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Rift Valley Fever (RVF) is an infectious illness with serious clinical manifestations and health consequences in humans as well as a wide range of domestic ruminants.
This review provides significant information about the prevention options of RVF along with the safety-efficacy profile of commercial vaccines and some of RVF vaccination strategies.
Information presented in this paper was obtained through a systematic investigation of published data about RVF vaccines.
Like other viral diseases, the prevention of RVF relies heavily on immunization of susceptible herds with safe and cost-effective vaccine that is able to confer long-term protective immunity.
Several strains of RVF vaccines have been developed and are available in commercial production including Formalin-Inactivated vaccine, live attenuated Smithburn vaccine, and the most recent Clone13.
Although Formalin-Inactivated vaccine and live attenuated Smithburn vaccine are immunogenic and widely used in prevention programs, they proved to be accompanied by significant concerns.
Despite Clone13 vaccine being suggested as safe in pregnant ewes and as highly immunogenic along with its potential for differentiating infected from vaccinated animals (DIVA), a recent study raised concerns about the safety of the vaccine during the first trimester of gestation.
Accordingly, RVF vaccines that are currently available in the market to a significant extent do not fulfill the requirements of safety, potency, and DIVA.
These adverse effects stressed the need for developing new vaccines with an excellent safety profile to bridge the gap in safety and immunity.
Bringing RVF vaccine candidates to local markets besides the absence of validated serological test for DIVA remain the major challenges of RVF control.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Alhaj, Moataz. 2016. Safety and Efficacy Profile of Commercial Veterinary Vaccines against Rift Valley Fever: A Review Study. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108869
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Alhaj, Moataz. Safety and Efficacy Profile of Commercial Veterinary Vaccines against Rift Valley Fever: A Review Study. Journal of Immunology Research No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1108869
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Alhaj, Moataz. Safety and Efficacy Profile of Commercial Veterinary Vaccines against Rift Valley Fever: A Review Study. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1108869
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108869
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر