High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica
المؤلفون المشاركون
Khaiboullina, Svetlana F.
Martynova, Ekaterina V.
Anokhin, Vladimir V.
Rizvanov, Albert A.
Valiullina, Aygul H.
Gusev, Oleg A.
Davidyuk, Yuriy N.
Garanina, Ekaterina E.
Shakirova, Venera G.
Khaertynova, Ilsiyar
المصدر
Journal of Immunology Research
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-12-05
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome.
Several reports have demonstrated a severe alteration in lipoprotein metabolism.
However, little is known about changes in circulating lipids in NE.
The objectives of this study were to evaluate changes in serum total cholesterol, high density cholesterol (HDCL), and triglycerides.
In addition to evaluation of serum cytokine activation associations, changes in lipid profile and cytokine activation were determined for gender, thrombocyte counts, and VEGF.
Elevated levels of triglycerides and decreased HDCL were observed in NE, while total cholesterol did not differ from controls.
High triglycerides were associated with both the lowest thrombocyte counts and high serum VEGF, as well as a high severity score.
Additionally, there were higher levels of triglycerides in male than female NE patients.
Low triglycerides were associated with upregulation of IFN-γ and IL-12, suggesting activation of Th1 helper cells.
Furthermore, levels of IFN-γ and IL-12 were increased in patients with lower severity scores, suggesting that a Th1 type immune response is playing protective role in NE.
These combined data advance the understanding of NE pathogenesis and indicate a role for high triglycerides in disease severity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Martynova, Ekaterina V.& Valiullina, Aygul H.& Gusev, Oleg A.& Davidyuk, Yuriy N.& Garanina, Ekaterina E.& Shakirova, Venera G.…[et al.]. 2016. High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica. Journal of Immunology Research،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108900
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Martynova, Ekaterina V.…[et al.]. High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica. Journal of Immunology Research No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1108900
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Martynova, Ekaterina V.& Valiullina, Aygul H.& Gusev, Oleg A.& Davidyuk, Yuriy N.& Garanina, Ekaterina E.& Shakirova, Venera G.…[et al.]. High Triglycerides Are Associated with Low Thrombocyte Counts and High VEGF in Nephropathia Epidemica. Journal of Immunology Research. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1108900
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1108900
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر