Immune Regulation and Antitumor Effect of TIM-1

الملخص EN

T cells play an important role in antitumor immunity, and the T cell immunoglobulin domain and the mucin domain protein-1 (TIM-1) on its surface, as a costimulatory molecule, has a strong regulatory effect on T cells.

TIM-1 can regulate and enhance type 1 immune response of tumor association.

Therefore, TIM-1 costimulatory pathways may be a promising therapeutic target in future tumor immunotherapy.

This review describes the immune regulation and antitumor effect of TIM-1.