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Gold Nanoparticles Synthesized with a Polyphenols-Rich Extract from Cornelian Cherry (Cornus mas) Fruits: Effects on Human Skin Cells
المؤلفون المشاركون
Florea, Adrian
David, Luminita
Perde-Schrepler, Maria
Olenic, Liliana
Potara, Monica
Fischer-Fodor, Eva
Virag, Piroska
Imre-Lucaci, Florica
Brie, Ioana
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-13
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Gold nanoparticles (GNPs) were obtained by green synthesis with an extract from Cornus mas fruits (GNPs-CM), characterized by several methods, and their biologic effects were evaluated on two cell lines: HaCaT, normal keratinocytes, and A431, epidermoid carcinoma.
GNPs were spherical with sizes between 2 and 24 nm.
Their optical spectra had a dominant plasmonic band centered at 525 nm; zeta potential distribution was narrow, centered at −19.7 mV, and the mean hydrodynamic diameter was 58 nm.
GNPs were visualized in both cell types entering the cells by endocytosis.
The amount of gold uptaken by the cells was dose and time dependent.
The intracellular concentration of Au ions was higher in HaCaT compared to A431 cells.
The toxicity of GNPs-CM was dose dependent being significant only when the highest concentrations were employed.
A431 cells were less affected compared to HaCaT cells, but the difference was not statistically significant.
ROS production was not significant, except in HaCaT cells at the highest concentration.
The comet assay revealed no significant supplementary DNA lesions, while the secretion of inflammatory cytokines was modulated by the presence of GNPs only when the cells were additionally irradiated with UVB.
These results recommend GNPs-CM for further testing and possible dermatological applications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Perde-Schrepler, Maria& David, Luminita& Olenic, Liliana& Potara, Monica& Fischer-Fodor, Eva& Virag, Piroska…[et al.]. 2016. Gold Nanoparticles Synthesized with a Polyphenols-Rich Extract from Cornelian Cherry (Cornus mas) Fruits: Effects on Human Skin Cells. Journal of Nanomaterials،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1109332
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Perde-Schrepler, Maria…[et al.]. Gold Nanoparticles Synthesized with a Polyphenols-Rich Extract from Cornelian Cherry (Cornus mas) Fruits: Effects on Human Skin Cells. Journal of Nanomaterials No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1109332
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Perde-Schrepler, Maria& David, Luminita& Olenic, Liliana& Potara, Monica& Fischer-Fodor, Eva& Virag, Piroska…[et al.]. Gold Nanoparticles Synthesized with a Polyphenols-Rich Extract from Cornelian Cherry (Cornus mas) Fruits: Effects on Human Skin Cells. Journal of Nanomaterials. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1109332
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1109332
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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