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Curcumin and Resveratrol as Promising Natural Remedies with Nanomedicine Approach for the Effective Treatment of Triple Negative Breast Cancer
المؤلفون المشاركون
Shindikar, Amol
Singh, Akshita
Nobre, Malcolm
Kirolikar, Saurabh
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-05-08
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Researchers have made considerable progress in last few decades in understanding mechanisms underlying pathogenesis of breast cancer, its phenotypes, its molecular and genetic changes, its physiology, and its prognosis.
This has allowed us to identify specific targets and design appropriate chemical entities for effective treatment of most breast cancer phenotypes, resulting in increased patient survivability.
Unfortunately, these strategies have been largely ineffective in the treatment of triple negative breast cancer (TNBC).
Hormonal receptors lacking render the conventional breast cancer drugs redundant, forcing scientists to identify novel targets for treatment of TNBC.
Two natural compounds, curcumin and resveratrol, have been widely reported to have anticancer properties.
In vitro and in vivo studies show promising results, though their effectiveness in clinical settings has been less than satisfactory, owing to their feeble pharmacokinetics.
Here we discuss these naturally occurring compounds, their mechanism as anticancer agents, their shortcomings in translational research, and possible methodology to improve their pharmacokinetics/pharmacodynamics with advanced drug delivery systems.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shindikar, Amol& Singh, Akshita& Nobre, Malcolm& Kirolikar, Saurabh. 2016. Curcumin and Resveratrol as Promising Natural Remedies with Nanomedicine Approach for the Effective Treatment of Triple Negative Breast Cancer. Journal of Oncology،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1109717
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shindikar, Amol…[et al.]. Curcumin and Resveratrol as Promising Natural Remedies with Nanomedicine Approach for the Effective Treatment of Triple Negative Breast Cancer. Journal of Oncology No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1109717
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shindikar, Amol& Singh, Akshita& Nobre, Malcolm& Kirolikar, Saurabh. Curcumin and Resveratrol as Promising Natural Remedies with Nanomedicine Approach for the Effective Treatment of Triple Negative Breast Cancer. Journal of Oncology. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1109717
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1109717
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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