A Randomized Controlled Trial of Conbercept Pretreatment before Vitrectomy in Proliferative Diabetic Retinopathy
المؤلفون المشاركون
Yang, Xiaochun
Xu, Jianbiao
Wang, Ruili
Mei, Yan
Lei, Huo
Liu, Jun
Zhang, Ting
Zhao, Haiyan
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-13
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To determine the efficacy and safety of preoperative intravitreal conbercept (IVC) injection before vitrectomy for proliferative diabetic retinopathy (PDR).
Methods.
107 eyes of 88 patients that underwent pars plana vitrectomy (PPV) for active PDR were enrolled.
All patients were assigned randomly to either preoperative IVC group or control group.
Follow-up examinations were performed for three months after surgery.
The primary bioactivity measures were severity of intraoperative bleeding, incidence of early and late recurrent VH, vitreous clear-up time, and best-corrected visual acuity (BCVA) levels.
The secondary safety measures included intraocular pressure, endophthalmitis, rubeosis, tractional retinal detachment, and systemic adverse events.
Results.
The incidence and severity of intraoperative bleeding were significantly lower in IVC group than in the control group.
The average vitreous clear-up time of early recurrent VH was significantly shorter in IVC group compared with that in control group.
There was no significant difference in vitreous clear-up time of late recurrent VH between the two groups.
Patients that received pretreatment of conbercept had much better BCVA at 3 days, 1 week, and 1 month after surgery than control group.
Moreover, both patients with improved BCVA were greater in IVC group than in control group at each follow-up.
Conclusions.
Conbercept pretreatment could be an effective adjunct to vitrectomy in accelerating postoperative vitreous clear-up and acquiring stable visual acuity restoration for PDR.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Xiaochun& Xu, Jianbiao& Wang, Ruili& Mei, Yan& Lei, Huo& Liu, Jun…[et al.]. 2016. A Randomized Controlled Trial of Conbercept Pretreatment before Vitrectomy in Proliferative Diabetic Retinopathy. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1109892
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Xiaochun…[et al.]. A Randomized Controlled Trial of Conbercept Pretreatment before Vitrectomy in Proliferative Diabetic Retinopathy. Journal of Ophthalmology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1109892
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Xiaochun& Xu, Jianbiao& Wang, Ruili& Mei, Yan& Lei, Huo& Liu, Jun…[et al.]. A Randomized Controlled Trial of Conbercept Pretreatment before Vitrectomy in Proliferative Diabetic Retinopathy. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1109892
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1109892
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر