Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis
المؤلفون المشاركون
Zheng, Xiaofen
Yao, Juan
Li, Bing
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-18
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The pathogenesis of allergic conjunctivitis has not been clearly established.
Moreover, previous studies fail to consider human models of allergic conjunctivitis.
This study investigated the expression of thymic stromal lymphopoiet in TSLP and its downstream molecules in conjunctival scrappings and tear.
Methods.
This cross-sectional study compares patients with vernal keratoconjunctivitis (VKC), seasonal allergic conjunctivitis (SAC), and perennial allergic conjunctivitis (PAC) with normal controls.
There are 80 people recorded in Shanxi Eye Hospital.
Increasingly, 20 are with VKC, 20 are with SAC, 20 are with PAC, and the remaining 20 are normal controls.
Conjunctiva were harvested for total RNA extraction and gene expression by real-time polymerase chain reaction.
Epithelial cells were collected to make pathological sections for immunohistochemical staining.
Human tears were evaluated by Luminex microbead assay.
A P value less than 0.05 from Dunnett’s post hoc test in SPSS means a statistical significant distinction.
Results.
Positive expression in conjunctival cells of patients with allergic conjunctivitis.
The expression of TSLP and IL-4, IL-5, and IL-13 mRNA shows a statistically significant difference ( P < 0.05 ).
TSLP and IL-4, IL-5, and IL-13 concentrations show a statistically significant difference ( P < 0.01 ).
Conclusions.
This study suggests that TSLP and downstream molecules are expressed in patients with various types of allergic conjunctivitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zheng, Xiaofen& Yao, Juan& Li, Bing. 2016. Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109981
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zheng, Xiaofen…[et al.]. Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1109981
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zheng, Xiaofen& Yao, Juan& Li, Bing. Expression of TSLP and Downstream Molecules IL-4, IL-5, and IL-13 on the Eye Surface of Patients with Various Types of Allergic Conjunctivitis. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1109981
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1109981
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر