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Scheimpflug Imaging Parameters Associated with Tear Mediators and Bronchial Asthma in Keratoconus
المؤلفون المشاركون
Fodor, Mariann
Gogolák, Péter
Berta, András
Csutak, Adrienne
Pásztor, Dorottya
Kolozsvári, Bence Lajos
Hassan, Ziad
Kettesy, Beáta Andrea
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-12
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Purpose.
To determine associations between mediators in tears in the whole spectrum of keratoconus (KC); to explore connections between mediators and Scheimpflug parameters; to examine correlations between Scheimpflug parameters and bronchial asthma.
Methods.
Tear samples were collected from 69 patients and 19 controls.
Concentrations of mediators—IL-6, -10; CXCL8, CCL5; MMP-9, -13; TIMP-1; t-PA, PAI-1—were measured by Cytometric Bead Array.
Measured Pentacam parameters include keratometry values (K1, K2, Kmax), corneal thickness (Pachy Pupil, Apex, Min), and elevations and indices (including Belin-Ambrósio deviation (BAD-D)).
Results.
A number of significant positive associations were observed between pairs of mediator concentrations.
Significant positive correlations were found between BAD-D and CXCL8/MMP-9 and K2 and MMP-9.
Significant negative associations were explored between Pachy Min and CXCL8/t-PA.
Significant associations were found between pairs of mediators (IL-6 and CXCL8; CCL5 and CXCL8/MMP-9; TIMP-1 and MMP-9/-13/t-PA; t-PA and CXCL8/CCL5/PAI-1) and the severity of KC.
Significant positive correlation between asthma and the severity of KC was explored.
Conclusion.
Cooperation of different mediators in tears all taking part in the complex pathomechanism of keratoconus was revealed.
Our research verifies that inflammation plays a crucial role in the pathogenesis of KC.
Additionally this study confirms the effect of bronchial asthma on keratoconus.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pásztor, Dorottya& Kolozsvári, Bence Lajos& Csutak, Adrienne& Berta, András& Hassan, Ziad& Kettesy, Beáta Andrea…[et al.]. 2016. Scheimpflug Imaging Parameters Associated with Tear Mediators and Bronchial Asthma in Keratoconus. Journal of Ophthalmology،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110123
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pásztor, Dorottya…[et al.]. Scheimpflug Imaging Parameters Associated with Tear Mediators and Bronchial Asthma in Keratoconus. Journal of Ophthalmology No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1110123
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pásztor, Dorottya& Kolozsvári, Bence Lajos& Csutak, Adrienne& Berta, András& Hassan, Ziad& Kettesy, Beáta Andrea…[et al.]. Scheimpflug Imaging Parameters Associated with Tear Mediators and Bronchial Asthma in Keratoconus. Journal of Ophthalmology. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1110123
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110123
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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