Candida Species Prevalence Profile in HIV Seropositive Patients from a Major Tertiary Care Hospital in New Delhi, India

الملخص EN

Candida is a common opportunistic pathogen during the course of human immunodeficiency virus (HIV) disease progression.

Changes in the clinical severity of candidiasis and the Candida species prevalence profile may be a reflection of immunological changes in HIV positive patients.

The aim of this study was to document the changing pattern of Candida species prevalence profile in HIV seropositive patients from a tertiary care hospital in North India.

One hundred and twenty HIV seropositive subjects were recruited for Candida microbial screening.

Clinical specimens including blood, oral swabs, expectorated or induced sputum/bronchoalveolar lavage specimens, and urine were collected depending on the patient’s symptoms.

A total of 128 Candida isolates were obtained from 88 cases and 7 different Candida species were identified.

C.

albicans (50%) was the most common species isolated followed by C.

glabrata (17%) and C.

dubliniensis (12.5%).

Other species isolated were C.

parapsilosis (7.8%), C.

krusei, C.

tropicalis (4.6% each), and C.

kefyr (3%).

Strong clinical suspicion along with optimal sampling of an accurate diagnosis of Candida species involved would go a long way in decreasing the morbidity associated with non-albicans Candida species.