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Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies
المؤلفون المشاركون
Bashir, Muhammad Faruk
Elechi, Hassan Abdullahi
Ashir, Mohammed Garba
Rabasa, Adamu Ibrahim
Bukbuk, David Nadeba
Usman, Ahmadu Baba
Mustapha, Modu Gofama
Alhaji, M. A.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Tetanus toxoid immunisation of pregnant mother has remained the most effective strategy in eliminating neonatal tetanus.
Impaired production and/or transplacental transfer of antibodies may affect the effectiveness of this strategy.
We studied the effect of maternal HIV infection on serum levels and transplacental transfer of anti-tetanus antibodies.
Methods.
A total of 162 mother-baby paired serum samples were taken and analysed for anti-tetanus antibody levels using ELISA.
Maternal HIV status was also determined by double ELISA technique.
Maternal TT vaccination status was also documented.
Results.
Thirty-eight (23.5%) mothers and 41 (25.3%) babies were seronegative, out of whom 8 mothers were HIV positive and 9 babies were HIV exposed.
HIV infected mothers and HIV exposed infants were, respectively, 16.27 times (OR = 16.27, 95% CI = 3.28 to 80.61) and 33.75 times (OR = 33.75, 95% CI = 4.12 to 276.40) more likely to be seronegative for anti-tetanus antibody.
Similarly, HIV positive mother-newborn pairs were 7.46 times more likely to have a poor transplacental transfer of tetanus antibodies (OR = 7.46, 95% CI = 1.96 to 28.41).
Conclusions.
Maternal HIV infection is associated with impaired maternofoetal transfer of anti-tetanus antibodies and seronegativity among mothers and their newborns.
Hence, this may hinder efforts to eliminate neonatal tetanus.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bashir, Muhammad Faruk& Elechi, Hassan Abdullahi& Ashir, Mohammed Garba& Rabasa, Adamu Ibrahim& Bukbuk, David Nadeba& Usman, Ahmadu Baba…[et al.]. 2016. Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies. Journal of Tropical Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110862
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bashir, Muhammad Faruk…[et al.]. Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies. Journal of Tropical Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1110862
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bashir, Muhammad Faruk& Elechi, Hassan Abdullahi& Ashir, Mohammed Garba& Rabasa, Adamu Ibrahim& Bukbuk, David Nadeba& Usman, Ahmadu Baba…[et al.]. Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies. Journal of Tropical Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110862
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110862
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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