Quality Assessment of Artemether-Lumefantrine Samples and Artemether Injections Sold in the Cape Coast Metropolis
المؤلفون المشاركون
Afoakwah, Richmond
Prah, James
Fiawoyife, Patrick
Oppong-Danquah, Ernest
Ameyaw, E. O.
Boampong, J. N.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-23
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Most prescribers and patients in Ghana now opt for the relatively expensive artemether/lumefantrine rather than artesunate-amodiaquine due to undesirable side effects in the treatment of uncomplicated malaria.
The study sought to determine the existence of substandard and/or counterfeit artemether-lumefantrine tablets and suspension as well as artemether injection on the market in Cape Coast.
Six brands of artemether-lumefantrine tablets, two brands of artemether-lumefantrine suspensions, and two brands of artemether injections were purchased from pharmacies in Cape Coast for the study.
The mechanical properties of the tablets were evaluated.
The samples were then analyzed for the content of active ingredients using High Performance Liquid Chromatography with a variable wavelength detector.
None of the samples was found to be counterfeit.
However, the artemether content of the samples was variable (93.22%−104.70% of stated content by manufacturer).
The lumefantrine content of the artemether/lumefantrine samples was also variable (98.70%–111.87%).
Seven of the artemether-lumefantrine brands passed whilst one failed the International Pharmacopoeia content requirements.
All brands of artemether injections sampled met the International Pharmacopoeia content requirement.
The presence of a substandard artemether-lumefantrine suspension in the market should alert regulatory bodies to be more vigilant and totally flush out counterfeit and substandard drugs from the Ghanaian market.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Prah, James& Ameyaw, E. O.& Afoakwah, Richmond& Fiawoyife, Patrick & Oppong-Danquah, Ernest & Boampong, J. N.. 2016. Quality Assessment of Artemether-Lumefantrine Samples and Artemether Injections Sold in the Cape Coast Metropolis. Journal of Tropical Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110865
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Prah, James…[et al.]. Quality Assessment of Artemether-Lumefantrine Samples and Artemether Injections Sold in the Cape Coast Metropolis. Journal of Tropical Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1110865
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Prah, James& Ameyaw, E. O.& Afoakwah, Richmond& Fiawoyife, Patrick & Oppong-Danquah, Ernest & Boampong, J. N.. Quality Assessment of Artemether-Lumefantrine Samples and Artemether Injections Sold in the Cape Coast Metropolis. Journal of Tropical Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110865
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110865
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر