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Antimalarial Potential of Carica papaya and Vernonia amygdalina in Mice Infected with Plasmodium berghei
المؤلفون المشاركون
Habila, Nathan
Okoduwa, Stanley I. R.
Okpe, Oche
Ikwebe, Joseph
Upev, Vincent A.
Isaac, Omiagocho T.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-11-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The study determined if administration of Vernonia amygdalina and Carica papaya plants provides synergistic effects in ameliorating plasmodium infection in mice.
Thirty mice (17.88–25.3 g) were divided into 6 groups of 5 mice each.
Group 1 was normal control, while groups 2–6 were intraperitoneally inoculated 2.5 × 107 Plasmodium berghei parasitized red blood cell, followed by daily administration of 350 mg/kg aqueous leaf extracts after establishment of infection.
Group 2 was disease control, while group 6 was treated with standard drug for four consecutive days.
The results showed significant ( P < 0.05 ) reduction in percentage of parasite load between the infected treatment groups and disease control group at day 3 after infection, which remained consistent until the end of the experiment.
All infected treated groups showed significant ( P < 0.05 ) increases in RBC and PCV recovery compared to the disease control, with the exception of WBC.
There was insignificant ( P > 0.05 ) change in mean body weight of all treated groups except in disease control group.
Histological studies of the infected mice indicate recovery of hepatic cells from congested black pigmentation.
The reduction in parasite load and recovery of hepatic cell damage/hematological parameters were induced by these plant extracts.
This highlighted the important usage of the plant in traditional remedy of malaria infection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Okpe, Oche& Habila, Nathan& Ikwebe, Joseph& Upev, Vincent A.& Okoduwa, Stanley I. R.& Isaac, Omiagocho T.. 2016. Antimalarial Potential of Carica papaya and Vernonia amygdalina in Mice Infected with Plasmodium berghei. Journal of Tropical Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110866
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Okpe, Oche…[et al.]. Antimalarial Potential of Carica papaya and Vernonia amygdalina in Mice Infected with Plasmodium berghei. Journal of Tropical Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1110866
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Okpe, Oche& Habila, Nathan& Ikwebe, Joseph& Upev, Vincent A.& Okoduwa, Stanley I. R.& Isaac, Omiagocho T.. Antimalarial Potential of Carica papaya and Vernonia amygdalina in Mice Infected with Plasmodium berghei. Journal of Tropical Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110866
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110866
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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