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Manipulation of Ovarian Function Significantly Influenced Sarcopenia in Postreproductive-Age Mice
المؤلفون المشاركون
Peterson, Rhett L.
Parkinson, Kate C.
Mason, Jeffrey B.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-22
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Previously, transplantation of ovaries from young cycling mice into old postreproductive-age mice increased life span.
We anticipated that the same factors that increased life span could also influence health span.
Female CBA/J mice received new (60 d) ovaries at 12 and 17 months of age and were evaluated at 16 and 25 months of age, respectively.
There were no significant differences in body weight among any age or treatment group.
The percentage of fat mass was significantly increased at 13 and 16 months of age but was reduced by ovarian transplantation in 16-month-old mice.
The percentages of lean body mass and total body water were significantly reduced in 13-month-old control mice but were restored in 16- and 25-month-old recipient mice by ovarian transplantation to the levels found in six-month-old control mice.
In summary, we have shown that skeletal muscle mass, which is negatively influenced by aging, can be positively influenced or restored by reestablishment of active ovarian function in aged female mice.
These findings provide strong incentive for further investigation of the positive influence of young ovaries on restoration of health in postreproductive females.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Peterson, Rhett L.& Parkinson, Kate C.& Mason, Jeffrey B.. 2016. Manipulation of Ovarian Function Significantly Influenced Sarcopenia in Postreproductive-Age Mice. Journal of Transplantation،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110894
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Peterson, Rhett L.…[et al.]. Manipulation of Ovarian Function Significantly Influenced Sarcopenia in Postreproductive-Age Mice. Journal of Transplantation No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1110894
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Peterson, Rhett L.& Parkinson, Kate C.& Mason, Jeffrey B.. Manipulation of Ovarian Function Significantly Influenced Sarcopenia in Postreproductive-Age Mice. Journal of Transplantation. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1110894
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110894
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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