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Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population
المؤلفون المشاركون
Pedersen, Mark R.
Choi, Myunghan
Brink, Jeffrey A.
Seetharam, Anil B.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-11-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Changes in distribution policies have increased median MELD at transplant with recipients requiring increasing intensive care perioperatively.
We aimed to evaluate association of preoperative variables with postoperative respiratory failure (PRF)/increased intensive care unit length of stay (ICU LOS)/short-term survival in a high MELD cohort undergoing liver transplant (LT).
Retrospective analysis identified cases of PRF and increased ICU LOS with recipient, donor, and surgical variables examined.
Variables were entered into regression with end points of PRF and ICU LOS > 3 days.
164 recipients were examined: 41 (25.0%) experienced PRF and 74 (45.1%) prolonged ICU LOS.
Significant predictors of PRF with univariate analysis: BMI > 30, pretransplant MELD, preoperative respiratory failure, LVEF < 50%, FVC < 80%, intraoperative transfusion > 6 units, warm ischemic time > 4 minutes, and cold ischemic time > 240 minutes.
On multivariate analysis, only pretransplant MELD predicted PRF (OR 1.14, p=0.01).
Significant predictors of prolonged ICU LOS with univariate analysis are as follows: pretransplant MELD, FVC < 80%, FEV1 < 80%, deceased donor, and cold ischemic time > 240 minutes.
On multivariate analysis, only pretransplant MELD predicted prolonged ICU LOS (OR 1.28, p<0.001).
One-year survival among cohorts with PRF and increased ICU LOS was similar to subjects without.
Pretransplant MELD is a robust predictor of PRF and ICU LOS.
Higher MELDs at LT are expected to increase need for ICU utilization and modify expectations for recovery in the immediate postoperative period.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pedersen, Mark R.& Choi, Myunghan& Brink, Jeffrey A.& Seetharam, Anil B.. 2016. Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population. Journal of Transplantation،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110895
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pedersen, Mark R.…[et al.]. Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population. Journal of Transplantation No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1110895
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pedersen, Mark R.& Choi, Myunghan& Brink, Jeffrey A.& Seetharam, Anil B.. Pretransplant Factors and Associations with Postoperative Respiratory Failure, ICU Length of Stay, and Short-Term Survival after Liver Transplantation in a High MELD Population. Journal of Transplantation. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1110895
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1110895
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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