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Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms
المؤلفون المشاركون
Ilmarinen, Pinja
Tuomisto, Leena E.
Kankaanranta, Hannu
Kauppi, Paula
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-23، 23ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-26
دولة النشر
مصر
عدد الصفحات
23
التخصصات الرئيسية
الملخص EN
Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an important factor in separating the phenotypes.
Most studies with asthma have been performed in patients being otherwise healthy.
However, in real life, comorbid diseases are very common in adult patients.
We review here the emerging comorbid conditions to asthma such as obesity, metabolic syndrome, diabetes mellitus type 2 (DM2), and cardiac and psychiatric diseases.
Their role as risk factors for incident asthma and whether they affect clinical asthma are evaluated.
Obesity, independently or as a part of metabolic syndrome, DM2, and depression are risk factors for incident asthma.
In contrast, the effects of comorbidities on clinical asthma are less well-known and mostly studies are lacking.
Cross-sectional studies in obese asthmatics suggest that they may have less well controlled asthma and worse lung function.
However, no long-term clinical follow-up studies with these comorbidities and asthma were identified.
These emerging comorbidities often occur in the same multimorbid adult patient and may have in common metabolic pathways and inflammatory or other alterations such as early life exposures, systemic inflammation, inflammasome, adipokines, hyperglycemia, hyperinsulinemia, lung mechanics, mitochondrial dysfunction, disturbed nitric oxide metabolism, and leukotrienes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kankaanranta, Hannu& Kauppi, Paula& Tuomisto, Leena E.& Ilmarinen, Pinja. 2016. Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-23.
https://search.emarefa.net/detail/BIM-1111028
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kankaanranta, Hannu…[et al.]. Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms. Mediators of Inflammation No. 2016 (2016), pp.1-23.
https://search.emarefa.net/detail/BIM-1111028
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kankaanranta, Hannu& Kauppi, Paula& Tuomisto, Leena E.& Ilmarinen, Pinja. Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-23.
https://search.emarefa.net/detail/BIM-1111028
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1111028
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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