Potential Use of Salivary Markers for Longitudinal Monitoring of Inflammatory Immune Responses to Vaccination
المؤلفون المشاركون
Sandalova, Elena
Garssen, Johan
Lim, Pei Wen
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-28
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Vaccination, designed to trigger a protective immune response against infection, is a trigger for mild inflammatory responses.
Vaccination studies can address the question of inflammation initiation, levels, and resolution as well as its regulation for respective studied pathogens.
Such studies largely based on analyzing the blood components including specific antibodies and cytokines were usually constrained by number of participants and volume of collected blood sample.
Hence, blood-based studies may not be able to cover the full dynamic range of inflammation responses induced by vaccination.
In this review, the potential of using saliva in addition to blood for studying the kinetics of inflammatory response studies was assessed.
Saliva sampling is noninvasive and has a great potential to be used for studies aimed at analysing the magnitude, time course, and variance in immune responses, including inflammation after vaccination.
Based on a literature survey of inflammatory biomarkers that can be determined in saliva and an analysis of how these biomarkers could help to understand the mechanisms and dynamics of immune reactivity and inflammation, we propose that the saliva-based approach might have potential to add substantial value to clinical studies, particularly in vulnerable populations such as infants, toddlers, and ill individuals.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lim, Pei Wen& Garssen, Johan& Sandalova, Elena. 2016. Potential Use of Salivary Markers for Longitudinal Monitoring of Inflammatory Immune Responses to Vaccination. Mediators of Inflammation،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1111183
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lim, Pei Wen…[et al.]. Potential Use of Salivary Markers for Longitudinal Monitoring of Inflammatory Immune Responses to Vaccination. Mediators of Inflammation No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1111183
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lim, Pei Wen& Garssen, Johan& Sandalova, Elena. Potential Use of Salivary Markers for Longitudinal Monitoring of Inflammatory Immune Responses to Vaccination. Mediators of Inflammation. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1111183
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1111183
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر