Lack of Association between Pulse Steroid Therapy and Bone Mineral Density in Patients with Multiple Sclerosis
المؤلفون المشاركون
Zengin Karahan, Serap
Boz, Cavit
Kilic, Sevgi
Can Usta, Nuray
Ozmenoglu, Mehmet
Altunayoglu Cakmak, Vildan
Gazioglu, Sibel
المصدر
Multiple Sclerosis International
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Multiple sclerosis (MS) has been associated with reduced bone mineral density (BMD).
The purpose of this study was to determine the possible factors affecting BMD in patients with MS.
We included consecutive 155 patients with MS and 90 age- and sex-matched control subjects.
Patients with MS exhibited significantly lower T-scores and Z-scores in the femoral neck and trochanter compared to the controls.
Ninety-four (61%) patients had reduced bone mass in either the lumbar spine or the femoral neck; of these, 64 (41.3%) had osteopenia and 30 (19.4%) had osteoporosis.
The main factors affecting BMD were disability, duration of MS, and smoking.
There was a negative relationship between femoral BMD and EDSS and disease duration.
No association with lumbar BMD was determined.
There were no correlations between BMD at any anatomic region and cumulative corticosteroid dose.
BMD is significantly lower in patients with MS than in healthy controls.
Reduced BMD in MS is mainly associated with disability and duration of the disease.
Short courses of high dose steroid therapy did not result in an obvious negative impact on BMD in the lumbar spine and femoral neck in patients with MS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zengin Karahan, Serap& Boz, Cavit& Kilic, Sevgi& Can Usta, Nuray& Ozmenoglu, Mehmet& Altunayoglu Cakmak, Vildan…[et al.]. 2016. Lack of Association between Pulse Steroid Therapy and Bone Mineral Density in Patients with Multiple Sclerosis. Multiple Sclerosis International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1112953
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zengin Karahan, Serap…[et al.]. Lack of Association between Pulse Steroid Therapy and Bone Mineral Density in Patients with Multiple Sclerosis. Multiple Sclerosis International No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1112953
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zengin Karahan, Serap& Boz, Cavit& Kilic, Sevgi& Can Usta, Nuray& Ozmenoglu, Mehmet& Altunayoglu Cakmak, Vildan…[et al.]. Lack of Association between Pulse Steroid Therapy and Bone Mineral Density in Patients with Multiple Sclerosis. Multiple Sclerosis International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1112953
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1112953
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر