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Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota
المؤلفون المشاركون
Madore, Charlotte
Leyrolle, Quentin
Lacabanne, Chloé
Benmamar-Badel, Anouk
Joffre, Corinne
Nadjar, Agnes
Layé, Sophie
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-10-20
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Several genetic causes of autism spectrum disorder (ASD) have been identified.
However, more recent work has highlighted that certain environmental exposures early in life may also account for some cases of autism.
Environmental insults during pregnancy, such as infection or malnutrition, seem to dramatically impact brain development.
Maternal viral or bacterial infections have been characterized as disruptors of brain shaping, even if their underlying mechanisms are not yet fully understood.
Poor nutritional diversity, as well as nutrient deficiency, is strongly associated with neurodevelopmental disorders in children.
For instance, imbalanced levels of essential fatty acids, and especially polyunsaturated fatty acids (PUFAs), are observed in patients with ASD and other neurodevelopmental disorders (e.g., attention deficit hyperactivity disorder (ADHD) and schizophrenia).
Interestingly, PUFAs, and specifically n-3 PUFAs, are powerful immunomodulators that exert anti-inflammatory properties.
These prenatal dietary and immunologic factors not only impact the fetal brain, but also affect the microbiota.
Recent work suggests that the microbiota could be the missing link between environmental insults in prenatal life and future neurodevelopmental disorders.
As both nutrition and inflammation can massively affect the microbiota, we discuss here how understanding the crosstalk between these three actors could provide a promising framework to better elucidate ASD etiology.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Madore, Charlotte& Leyrolle, Quentin& Lacabanne, Chloé& Benmamar-Badel, Anouk& Joffre, Corinne& Nadjar, Agnes…[et al.]. 2016. Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota. Neural Plasticity،Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1113098
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Madore, Charlotte…[et al.]. Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota. Neural Plasticity No. 2016 (2016), pp.1-15.
https://search.emarefa.net/detail/BIM-1113098
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Madore, Charlotte& Leyrolle, Quentin& Lacabanne, Chloé& Benmamar-Badel, Anouk& Joffre, Corinne& Nadjar, Agnes…[et al.]. Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1113098
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113098
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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