![](/images/graphics-bg.png)
Inducing LTD-Like Effect in the Human Motor Cortex with Low Frequency and Very Short Duration Paired Associative Stimulation: An Exploratory Study
المؤلفون المشاركون
Srivanitchapoom, Prachaya
Park, Jung E.
Thirugnanasambandam, Nivethida
Panyakaew, Pattamon
Ramos, Vesper Fe Marie
Pandey, Sanjay
Wu, Tianxia
Hallett, Mark
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Introduction.
Paired associative stimulation (PAS) is an established technique to investigate synaptic plasticity in the human motor cortex (M1).
Classically, to induce long-term depression- (LTD-) or long-term potentiation-like effects in the human M1, studies have used low frequency and long duration trains of PAS.
In the present study, we explored an LTD-like effect using very short duration and low frequency of P A S 10 m s protocols in human M1.
Methods.
Six protocols of low frequency P A S 10 m s (ranging from 0.2 Hz to 1 Hz) were investigated with very short durations of 1 and 2 minutes stimulation.
Six healthy volunteers were included in each protocol.
We obtained motor-evoked potentials from right abductor pollicis brevis muscle before and after applying P A S 10 m s up to 30 minutes.
After we found P A S 10 m s protocol which induced an LTD-like effect, we tested that protocol on additional 5 subjects.
Results.
One-way repeated-measures ANOVA showed that only the group of 1-minute stimulation of 0.25 Hz induced an LTD-like effect.
When adding the additional subjects, the effect remained and lasted for 30 minutes.
Conclusion.
Low frequency and very short duration of P A S 10 m s potentially induced an LTD-like effect in human M1.
With further verification, this method might be useful for research relating to synaptic plasticity by reducing the duration of study and minimizing subject discomfort.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Srivanitchapoom, Prachaya& Park, Jung E.& Thirugnanasambandam, Nivethida& Panyakaew, Pattamon& Ramos, Vesper Fe Marie& Pandey, Sanjay…[et al.]. 2016. Inducing LTD-Like Effect in the Human Motor Cortex with Low Frequency and Very Short Duration Paired Associative Stimulation: An Exploratory Study. Neural Plasticity،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113115
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Srivanitchapoom, Prachaya…[et al.]. Inducing LTD-Like Effect in the Human Motor Cortex with Low Frequency and Very Short Duration Paired Associative Stimulation: An Exploratory Study. Neural Plasticity No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1113115
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Srivanitchapoom, Prachaya& Park, Jung E.& Thirugnanasambandam, Nivethida& Panyakaew, Pattamon& Ramos, Vesper Fe Marie& Pandey, Sanjay…[et al.]. Inducing LTD-Like Effect in the Human Motor Cortex with Low Frequency and Very Short Duration Paired Associative Stimulation: An Exploratory Study. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113115
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113115
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)