![](/images/graphics-bg.png)
Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus
المؤلفون المشاركون
Salois, Garrick
Smith, Jeffrey S.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-02-18
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Rats used in research are typically housed singly in cages with limited sensory stimulation.
There is substantial evidence that housing rats in these conditions lead to numerous neuroanatomical and behavioral abnormalities.
Alternatively, rats can be housed in an enriched environment in which rats are housed in groups and given room for exercise and exploration.
Enriched environments result in considerable neuroplasticity in the rodent brain.
In the dentate gyrus of the hippocampus, enriched environments evoke especially profound neural changes, including increases in the number of neurons and the number of dendritic spines.
However, whether changes in astrocytes, a type of glia increasingly implicated in mediating neuroplasticity, are concurrent with these neural changes remains to be investigated.
In order to assess morphological changes among astrocytes of the rat dentate gyrus, piSeeDB was used to optically clear 250 μm sections of tissue labeled using GFAP immunohistochemistry.
Confocal imaging and image analysis were then used to measure astrocyte morphology.
Astrocytes from animals housed in EE demonstrated a reduced distance between filament branch points.
Furthermore, the most complex astrocytes were significantly more complex among animals housed in EE compared to standard environments.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Salois, Garrick& Smith, Jeffrey S.. 2016. Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus. Neural Plasticity،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113117
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Salois, Garrick& Smith, Jeffrey S.. Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus. Neural Plasticity No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1113117
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Salois, Garrick& Smith, Jeffrey S.. Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113117
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113117
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)