Parietal Fast Sleep Spindle Density Decrease in Alzheimer’s Disease and Amnesic Mild Cognitive Impairment
المؤلفون المشاركون
De Gennaro, Luigi
Gorgoni, Maurizio
Lauri, Giulia
Truglia, Ilaria
Cordone, Susanna
Sarasso, Simone
Scarpelli, Serena
Mangiaruga, Anastasia
Tempesta, Daniela
Ferrara, Michele
Rossini, Paolo Maria
Marra, Camillo
D'Atri, Aurora
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-15
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Several studies have identified two types of sleep spindles: fast (13–15 Hz) centroparietal and slow (11–13 Hz) frontal spindles.
Alterations in spindle activity have been observed in Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI).
Only few studies have separately assessed fast and slow spindles in these patients showing a reduction of fast spindle count, but the possible local specificity of this phenomenon and its relation to cognitive decline severity are not clear.
Moreover, fast and slow spindle density have never been assessed in AD/MCI.
We have assessed fast and slow spindles in 15 AD patients, 15 amnesic MCI patients, and 15 healthy elderly controls (HC).
Participants underwent baseline polysomnographic recording (19 cortical derivations).
Spindles during nonrapid eye movements sleep were automatically detected, and spindle densities of the three groups were compared in the derivations where fast and slow spindles exhibited their maximum expression (parietal and frontal, resp.).
AD and MCI patients showed a significant parietal fast spindle density decrease, positively correlated with Minimental State Examination scores.
Our results suggest that AD-related changes in spindle density are specific for frequency and location, are related to cognitive decline severity, and may have an early onset in the pathology development.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gorgoni, Maurizio& Lauri, Giulia& Truglia, Ilaria& Cordone, Susanna& Sarasso, Simone& Scarpelli, Serena…[et al.]. 2016. Parietal Fast Sleep Spindle Density Decrease in Alzheimer’s Disease and Amnesic Mild Cognitive Impairment. Neural Plasticity،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1113336
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gorgoni, Maurizio…[et al.]. Parietal Fast Sleep Spindle Density Decrease in Alzheimer’s Disease and Amnesic Mild Cognitive Impairment. Neural Plasticity No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1113336
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gorgoni, Maurizio& Lauri, Giulia& Truglia, Ilaria& Cordone, Susanna& Sarasso, Simone& Scarpelli, Serena…[et al.]. Parietal Fast Sleep Spindle Density Decrease in Alzheimer’s Disease and Amnesic Mild Cognitive Impairment. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1113336
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113336
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر