Distinctive Structural and Effective Connectivity Changes of Semantic Cognition Network across Left and Right Mesial Temporal Lobe Epilepsy Patients
المؤلفون المشاركون
Shan, Yi
Yan, Hao
Fan, Xiaotong
Shang, Kun
Wang, Xiaocui
Wang, Peipei
Shan, Yongzhi
Zhao, Guoguang
Lu, Jie
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-11-29
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Occurrence of language impairment in mesial temporal lobe epilepsy (mTLE) patients is common and left mTLE patients always exhibit a primary problem with access to names.
To explore different neuropsychological profiles between left and right mTLE patients, the study investigated both structural and effective functional connectivity changes within the semantic cognition network between these two groups and those from normal controls.
We found that gray matter atrophy of left mTLE patients was more severe than that of right mTLE patients in the whole brain and especially within the semantic cognition network in their contralateral hemisphere.
It suggested that seizure attacks were rather targeted than random for patients with hippocampal sclerosis (HS) in the dominant hemisphere.
Functional connectivity analysis during resting state fMRI revealed that subregions of the anterior temporal lobe (ATL) in the left HS patients were no longer effectively connected.
Further, we found that, unlike in right HS patients, increased causal linking between ipsilateral regions in the left HS epilepsy patients cannot make up for their decreased contralateral interaction.
It suggested that weakened contralateral connection and disrupted effective interaction between subregions of the unitary, transmodal hub of the ATL may be the primary cause of anomia in the left HS patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fan, Xiaotong& Yan, Hao& Shan, Yi& Shang, Kun& Wang, Xiaocui& Wang, Peipei…[et al.]. 2016. Distinctive Structural and Effective Connectivity Changes of Semantic Cognition Network across Left and Right Mesial Temporal Lobe Epilepsy Patients. Neural Plasticity،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113347
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fan, Xiaotong…[et al.]. Distinctive Structural and Effective Connectivity Changes of Semantic Cognition Network across Left and Right Mesial Temporal Lobe Epilepsy Patients. Neural Plasticity No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1113347
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fan, Xiaotong& Yan, Hao& Shan, Yi& Shang, Kun& Wang, Xiaocui& Wang, Peipei…[et al.]. Distinctive Structural and Effective Connectivity Changes of Semantic Cognition Network across Left and Right Mesial Temporal Lobe Epilepsy Patients. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113347
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113347
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر