Lycopene Deficiency in Ageing and Cardiovascular Disease
المؤلف
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-01-06
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Lycopene is a hydrocarbon phytochemical belonging to the tetraterpene carotenoid family and is found in red fruit and vegetables.
Eleven conjugated double bonds predetermine the antioxidant properties of lycopene and its ability to scavenge lipid peroxyl radicals, reactive oxygen species, and nitric oxide.
Lycopene has a low bioavailability rate and appears in the blood circulation incorporated into chylomicrons and other apo-B containing lipoproteins.
The recent body of evidence suggests that plasma concentration of lycopene is not only a function of intestinal absorption rate but also lycopene breakdown via enzymatic and oxidative pathways in blood and tissues.
Oxidative stress and the accumulation of reactive oxygen species and nitric oxide may represent a major cause of lycopene depletion in ageing, cardiovascular disease, and type 2 diabetes mellitus.
It has been shown recently that low carotenoid levels, and especially decreased serum lycopene levels, are strongly predictive of all-cause mortality and poor outcomes of cardiovascular disease.
However, there is a poor statistical association between dietary and serum lycopene levels which occurs due to limited bioavailability of lycopene from dietary sources.
Hence, it is very unlikely that nutritional intervention alone could be instrumental in the correction of lycopene and carotenoid deficiency.
Therefore, new nutraceutical formulations of carotenoids with enhanced bioavailability are urgently needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Petyaev, Ivan M.. 2016. Lycopene Deficiency in Ageing and Cardiovascular Disease. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1113794
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Petyaev, Ivan M.. Lycopene Deficiency in Ageing and Cardiovascular Disease. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1113794
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Petyaev, Ivan M.. Lycopene Deficiency in Ageing and Cardiovascular Disease. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1113794
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113794
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر