Implications of Hydrogen Sulfide in Glucose Regulation: How H2S Can Alter Glucose Homeostasis through Metabolic Hormones
المؤلفون المشاركون
Pichette, Jennifer
Gagnon, Jeffrey
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-07-11
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Diabetes and its comorbidities continue to be a major health problem worldwide.
Understanding the precise mechanisms that control glucose homeostasis and their dysregulation during diabetes are a major research focus.
Hydrogen sulfide (H2S) has emerged as an important regulator of glucose homeostasis.
This is achieved through its production and action in several metabolic and hormone producing organs including the pancreas, liver, and adipose.
Of importance, H2S production and signaling in these tissues are altered during both type 1 and type 2 diabetes mellitus.
This review first examines how H2S is produced both endogenously and by gastrointestinal microbes, with a particular focus on the altered production that occurs during obesity and diabetes.
Next, the action of H2S on the metabolic organs with key roles in glucose homeostasis, with a particular focus on insulin, is described.
Recent work has also suggested that the effects of H2S on glucose homeostasis goes beyond its role in insulin secretion.
Several studies have demonstrated important roles for H2S in hepatic glucose output and adipose glucose uptake.
The mechanism of H2S action on these metabolic organs is described.
In the final part of this review, future directions examining the roles of H2S in other metabolic and glucoregulatory hormone secreting tissues are proposed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pichette, Jennifer& Gagnon, Jeffrey. 2016. Implications of Hydrogen Sulfide in Glucose Regulation: How H2S Can Alter Glucose Homeostasis through Metabolic Hormones. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1113799
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pichette, Jennifer& Gagnon, Jeffrey. Implications of Hydrogen Sulfide in Glucose Regulation: How H2S Can Alter Glucose Homeostasis through Metabolic Hormones. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1113799
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pichette, Jennifer& Gagnon, Jeffrey. Implications of Hydrogen Sulfide in Glucose Regulation: How H2S Can Alter Glucose Homeostasis through Metabolic Hormones. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1113799
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113799
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر