Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats
المؤلفون المشاركون
Gun, Aburrahman
Ozer, Mehmet Kaya
Bilgic, Sedat
Kocaman, Nevin
Ozan, Gonca
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Fructose corn syrup is cheap sweetener and prolongs the shelf life of products, but fructose intake causes hyperinsulinemia, hypertriglyceridemia, and hypertension.
All of them are referred to as metabolic syndrome and they are risk factors for cardiovascular diseases.
Hence, the harmful effects of increased fructose intake on health and their prevention should take greater consideration.
Caffeic Acid Phenethyl Ester (CAPE) has beneficial effects on metabolic syndrome and vascular function which is important in the prevention of cardiovascular disease.
However, there are no known studies about the effect of CAPE on fructose-induced vascular dysfunction.
In this study, we examined the effect of CAPE on vascular dysfunction due to high fructose corn syrup (HFCS).
HFCS (6 weeks, 30% fed with drinking water) caused vascular dysfunction, but treatment with CAPE (50 micromol/kg i.p.
for the last two weeks) effectively restored this problem.
Additionally, hypertension in HFCS-fed rats was also decreased in CAPE supplemented rats.
CAPE supplements lowered HFCS consumption-induced raise in blood glucose, homocysteine, and cholesterol levels.
The aorta tissue endothelial nitric oxide synthase (eNOS) production was decreased in rats given HFCS and in contrast CAPE supplementation efficiently increased its production.
The presented results showed that HFCS-induced cardiovascular abnormalities could be prevented by CAPE treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gun, Aburrahman& Ozer, Mehmet Kaya& Bilgic, Sedat& Kocaman, Nevin& Ozan, Gonca. 2016. Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113811
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gun, Aburrahman…[et al.]. Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1113811
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gun, Aburrahman& Ozer, Mehmet Kaya& Bilgic, Sedat& Kocaman, Nevin& Ozan, Gonca. Effect of Caffeic Acid Phenethyl Ester on Vascular Damage Caused by Consumption of High Fructose Corn Syrup in Rats. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113811
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113811
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر