Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver
المؤلفون المشاركون
Wozniak, Michal
Antosiewicz, J.
Flis, Damian Jozef
Olek, Robert Antoni
Kaczor, Jan Jacek
Rodziewicz, Ewa
Halon, Malgorzata
Gabbianelli, Rosita
Ziolkowski, Wieslaw
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The reduction in cholesterol in mitochondria, observed after exercise, is related to the inhibition of mitochondrial swelling.
Caveolin-1 (Cav-1) plays an essential role in the regulation of cellular cholesterol metabolism and is required by various signalling pathways.
Therefore, the aim of this study was to investigate the effect of prolonged swimming on the mitochondrial Cav-1 concentration; additionally, we identified the results of these changes as they relate to the induction of changes in the mitochondrial swelling and cholesterol in rat skeletal muscle and liver.
Male Wistar rats were divided into a sedentary control group and an exercise group.
The exercised rats swam for 3 hours and were burdened with an additional 3% of their body weight.
After the cessation of exercise, their quadriceps femoris muscles and livers were immediately removed for experimentation.
The exercise protocol caused an increase in the Cav-1 concentration in crude muscle mitochondria; this was related to a reduction in the cholesterol level and an inhibition of mitochondrial swelling.
There were no changes in rat livers, with the exception of increased markers of oxidative stress in mitochondria.
These data indicate the possible role of Cav-1 in the adaptive change in the rat muscle mitochondria following exercise.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Flis, Damian Jozef& Olek, Robert Antoni& Kaczor, Jan Jacek& Rodziewicz, Ewa& Halon, Malgorzata& Antosiewicz, J.…[et al.]. 2015. Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113845
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Flis, Damian Jozef…[et al.]. Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1113845
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Flis, Damian Jozef& Olek, Robert Antoni& Kaczor, Jan Jacek& Rodziewicz, Ewa& Halon, Malgorzata& Antosiewicz, J.…[et al.]. Exercise-Induced Changes in Caveolin-1, Depletion of Mitochondrial Cholesterol, and the Inhibition of Mitochondrial Swelling in Rat Skeletal Muscle but Not in the Liver. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113845
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1113845
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر