Diagnostic, Prognostic, and Therapeutic Value of Circulating miRNAs in Heart Failure Patients Associated with Oxidative Stress
المؤلفون المشاركون
Zhuang, Jian
Sayed, Ali Sheikh Md
Salma, Umme
Zhang, Baohai
Chen, Jimei
Ping, Zhu
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-06-09
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Heart failure is a major public health problem especially in the aging population (≥65 years old), affecting nearly 5 million Americans and 15 million European people.
Effective management of heart failure (HF) depends on a correct and rapid diagnosis.
Presently, BNP (brain natriuretic peptide) or N-terminal pro-brain natriuretic peptide (NT-proBNP) assay is generally accepted by the international community for diagnostic evaluation and risk stratification of patients with HF.
However, regardless of its widespread clinical use, BNP is still encumbered by reduced specificity.
As a result, diagnosis of heart failure remains challenging.
Although significant improvement happened in the clinical management of HF over the last 2 decades, traditional treatments are ultimately ineffective in many patients who progress to advanced HF.
Therefore, a novel diagnostic, prognostic biomarker and new therapeutic approach are required for clinical management of HF patients.
Circulating miRNAs seem to be the right choice for novel noninvasive biomarkers as well as new treatment strategies for HF.
In this review, we briefly discuss the diagnostic, prognostic, and therapeutic role of circulating miRNAs in heart failure patients.
We also mentioned our own technique of extraction of RNA and detection of circulating miRNAs from human plasma and oxidative stress associated miRNAs with HF.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sayed, Ali Sheikh Md& Salma, Umme& Zhang, Baohai& Chen, Jimei& Zhuang, Jian& Ping, Zhu. 2016. Diagnostic, Prognostic, and Therapeutic Value of Circulating miRNAs in Heart Failure Patients Associated with Oxidative Stress. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1114065
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sayed, Ali Sheikh Md…[et al.]. Diagnostic, Prognostic, and Therapeutic Value of Circulating miRNAs in Heart Failure Patients Associated with Oxidative Stress. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1114065
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sayed, Ali Sheikh Md& Salma, Umme& Zhang, Baohai& Chen, Jimei& Zhuang, Jian& Ping, Zhu. Diagnostic, Prognostic, and Therapeutic Value of Circulating miRNAs in Heart Failure Patients Associated with Oxidative Stress. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1114065
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114065
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر