Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases
المؤلفون المشاركون
Sciarretta, Sebastiano
Frati, G.
Conti, V.
Vecchione, Carmine
Forte, Maurizio
Damato, Antonio
Ambrosio, Mariateresa
Puca, Annibale A.
Carrizzo, Albino
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-20، 20ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-29
دولة النشر
مصر
عدد الصفحات
20
التخصصات الرئيسية
الملخص EN
Within the family of endogenous gasotransmitters, nitric oxide (NO) is the smallest gaseous intercellular messenger involved in the modulation of several processes, such as blood flow and platelet aggregation control, essential to maintain vascular homeostasis.
NO is produced by nitric oxide synthases (NOS) and its effects are mediated by cGMP-dependent or cGMP-independent mechanisms.
Growing evidence suggests a crosstalk between the NO signaling and the occurrence of oxidative stress in the onset and progression of vascular diseases, such as hypertension, heart failure, ischemia, and stroke.
For these reasons, NO is considered as an emerging molecular target for developing therapeutic strategies for cardio- and cerebrovascular pathologies.
Several natural derived compounds, such as polyphenols, are now proposed as modulators of NO-mediated pathways.
The aim of this review is to highlight the experimental evidence on the involvement of nitric oxide in vascular homeostasis focusing on the therapeutic potential of targeting NO with some natural compounds in patients with vascular diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Forte, Maurizio& Conti, V.& Damato, Antonio& Ambrosio, Mariateresa& Puca, Annibale A.& Sciarretta, Sebastiano…[et al.]. 2016. Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-20.
https://search.emarefa.net/detail/BIM-1114187
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Forte, Maurizio…[et al.]. Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-20.
https://search.emarefa.net/detail/BIM-1114187
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Forte, Maurizio& Conti, V.& Damato, Antonio& Ambrosio, Mariateresa& Puca, Annibale A.& Sciarretta, Sebastiano…[et al.]. Targeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular Diseases. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-20.
https://search.emarefa.net/detail/BIM-1114187
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114187
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر