Phytochemical Composition, Antifungal and Antioxidant Activity of Duguetia furfuracea A. St.-Hill
المؤلفون المشاركون
Douglas Melo Coutinho, Henrique
Sobral de Souza, Celestina Elba
Valéria Soares de Araújo Pinho, Francisca
Franco, Jeferson Luis
Posser, Thaís
Boligon, Aline Augusti
da Cruz, Litiele Cezar
Rodrigues, Nathane Rosa
Waczuk, Emily Pansera
Costa, José Galberto Martins da
de Menezes, Irwin Rose Alencar
Athayde, Margareth Linde
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-04-05
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Duguetia furfuracea is popular plant used in popular medicine.
Hypothesis/Purpose.
This claim evaluated the phytochemical composition of the hydroethanolic extract (HEDF), fractions of Duguetia furfuracea, and antioxidant and antifungal activity.
Methods.
The chemical profile was carried out by HPLC-DAD.
The total phenolic contents and flavonoid components were determined by Folin-Ciocalteu and aluminium chloride reaction.
The antioxidant activity was measured by scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical and ferric reducing ability of plasma (FRAP) methods.
The antifungal activity was determined by microdilution assay.
Results.
HPLC analysis revealed caffeic acid and rutin as major compounds (HEDF), caffeic acid and quercitrin (Mt-OH fraction), and quercitrin and isoquercitrin (Ac-OEt fraction).
The highest levels of phenols and total flavonoids were found for Ac-OEt fraction, and the crude extract showed higher in vitro antioxidant potential.
The antifungal activity showed synergic effect with fluconazole and EHDF against C.
krusei, fluconazole and Mt-OH against C.
krusei and C.
tropicalis, and Ac-OE and fluconazole against C.
albicans.
Conclusion.
The highest levels of phenols and total flavonoids were marked with antioxidant effect.
This is the first report of bioactivity of the synergic effect of HEDF and fractions.
More studies would be required to better clarify its mechanism of synergic action.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Valéria Soares de Araújo Pinho, Francisca& da Cruz, Litiele Cezar& Rodrigues, Nathane Rosa& Waczuk, Emily Pansera& Sobral de Souza, Celestina Elba& Douglas Melo Coutinho, Henrique…[et al.]. 2016. Phytochemical Composition, Antifungal and Antioxidant Activity of Duguetia furfuracea A. St.-Hill. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114244
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Valéria Soares de Araújo Pinho, Francisca…[et al.]. Phytochemical Composition, Antifungal and Antioxidant Activity of Duguetia furfuracea A. St.-Hill. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1114244
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Valéria Soares de Araújo Pinho, Francisca& da Cruz, Litiele Cezar& Rodrigues, Nathane Rosa& Waczuk, Emily Pansera& Sobral de Souza, Celestina Elba& Douglas Melo Coutinho, Henrique…[et al.]. Phytochemical Composition, Antifungal and Antioxidant Activity of Duguetia furfuracea A. St.-Hill. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114244
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1114244
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر